The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

dnaA  -  chromosomal replication initiation protein...

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of dnaA

 

High impact information on dnaA

  • The suppressor phenotype is also sensitive to modulation by the dnaA genotype [2].
  • Obviously the temperature sensitive function of the dnaA-product is dispensable for P22 DNA replication, especially for its initiation [3].
  • Additional evidence suggesting that the cryptic plasmid controls its own initiation of replication independently of the function of the chromosomal dnaA gene is supplied by the results of the determination of incorporation of labelled thymidine into CCC DNA of the dnaA1 strain at the nonpermissive temperature [4].
  • It is suggested that the cryptic plasmid may integrate into the chromosome of S. typhimurium and this integration may result in suppression of the dnaA mutation [4].
  • Suppression of dnaA mutation by F'lac and cryptic LT2 plasmid was used for selecting clones containing these plasmids integrated into rfa and galK genes [5].

References

 
WikiGenes - Universities