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Gene Review

Dgka  -  diacylglycerol kinase, alpha

Rattus norvegicus

Synonyms: 80 kDa diacylglycerol kinase, DAG kinase alpha, DGK-alpha, Dagk, Dagk1, ...
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High impact information on Dgka


Biological context of Dgka

  • The enzyme translocation is not directly linked to phosphoinositide turnover and protein phosphorylation, since phorbol myristate acetate and calcium ionophore did not affect the cellular DGK alpha and since we detected no covalent modification of the enzyme molecule [3].

Anatomical context of Dgka


  1. Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons. Goto, K., Kondo, H. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  2. Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol. Koya, D., Lee, I.K., Ishii, H., Kanoh, H., King, G.L. J. Am. Soc. Nephrol. (1997) [Pubmed]
  3. Translocation of diacylglycerol kinase alpha to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes. Wada, I., Kai, M., Imai, S., Sakane, F., Kanoh, H. FEBS Lett. (1996) [Pubmed]
  4. Gene cloning, sequence, expression and in situ localization of 80 kDa diacylglycerol kinase specific to oligodendrocyte of rat brain. Goto, K., Watanabe, M., Kondo, H., Yuasa, H., Sakane, F., Kanoh, H. Brain Res. Mol. Brain Res. (1992) [Pubmed]
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