The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

FAM84A  -  family with sequence similarity 84, member A

Homo sapiens

Synonyms: FLJ35392, NSE1, Neurologic sensory protein 1, PP11517, Protein FAM84A
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of FAM84A

  • A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells [1].
 

High impact information on FAM84A

  • Our results indicate a possibility that up-regulation of FAM84A plays a critical role in progression of colon cancer [1].
  • In addition, we found that exogenous FAM84A expression increased cell motility in NIH3T3 cells, and that phosphorylation of serine 38 of FAM84A was associated with morphology of cells [1].
  • One of these was a gene termed FAM84A that was not expressed in any of the 23 normal tissues examined except the testis [1].
  • On the contrary, NSE1 and GAS mRNAs were not detected either in patient or in control blood samples; however, they were abundantly expressed in normal and cancerous colon mucosa, encouraging further search for useful markers able to detect epithelial cells in peripheral blood [2].

References

  1. A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., Nakamura, Y. Int. J. Oncol. (2006) [Pubmed]
  2. Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. Solmi, R., De Sanctis, P., Zucchini, C., Ugolini, G., Rosati, G., Del Governatore, M., Coppola, D., Yeatman, T.J., Lenzi, L., Caira, A., Zanotti, S., Taffurelli, M., Carinci, P., Valvassori, L., Strippoli, P. Int. J. Oncol. (2004) [Pubmed]
 
WikiGenes - Universities