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Gene Review

lem-2  -  Protein LEM-2

Caenorhabditis elegans

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Disease relevance of lem-2


High impact information on lem-2


Biological context of lem-2


Anatomical context of lem-2


Other interactions of lem-2


  1. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans. Liu, J., Lee, K.K., Segura-Totten, M., Neufeld, E., Wilson, K.L., Gruenbaum, Y. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  2. Barrier-to-autointegration factor is required to segregate and enclose chromosomes within the nuclear envelope and assemble the nuclear lamina. Margalit, A., Segura-Totten, M., Gruenbaum, Y., Wilson, K.L. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  3. A lamin-dependent pathway that regulates nuclear organization, cell cycle progression and germ cell development. Margalit, A., Liu, J., Fridkin, A., Wilson, K.L., Gruenbaum, Y. Novartis Found. Symp. (2005) [Pubmed]
  4. Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro. Holaska, J.M., Lee, K.K., Kowalski, A.K., Wilson, K.L. J. Biol. Chem. (2003) [Pubmed]
  5. C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis. Lee, K.K., Gruenbaum, Y., Spann, P., Liu, J., Wilson, K.L. Mol. Biol. Cell (2000) [Pubmed]
  6. Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans. Lee, K.K., Starr, D., Cohen, M., Liu, J., Han, M., Wilson, K.L., Gruenbaum, Y. Mol. Biol. Cell (2002) [Pubmed]
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