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Gene Review:

Nov - nephroblastoma overexpressed gene

Mus musculus

Synonyms: C130088N23Rik, CCN family member 3, CCN3, Ccn3, Nephroblastoma-overexpressed gene protein homolog, ...

Natarajan, D. et al., Rydziel, S. et al.

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Disease relevance of Nov

Nov transgenic mice exhibited osteopenia [1].

High impact information on Nov

Mouse Nov gene is expressed in hypaxial musculature and cranial structures derived from neural crest cells and placodes [2].
In the nervous system, Nov is observed in the somatic motor neurons of the spinal cord from 12.5 dpc and in cranial structures derived either from neural crest cells or placodes, including V, VII, VIII, and IX ganglia and olfactory neuroepithelia [2].

References

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. Rydziel, S., Stadmeyer, L., Zanotti, S., Durant, D., Smerdel-Ramoya, A., Canalis, E. J. Biol. Chem. (2007) [Pubmed]
Mouse Nov gene is expressed in hypaxial musculature and cranial structures derived from neural crest cells and placodes. Natarajan, D., Andermarcher, E., Schofield, P.N., Boulter, C.A. Dev. Dyn. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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NOV	Gallus gallus
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