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Gene Review

Rab17  -  RAB17, member RAS oncogene family

Mus musculus

Synonyms: AW413472, Ras-related protein Rab-17
 
 
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High impact information on Rab17

  • Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells [1].
  • Here we report the genetic mapping of Rab17 and Rab18 on mouse chromosomes 1 and 18, respectively [2].
  • We summarize here data on the presence and the functional role of vesicle transport proteins in the kidney, and describe work addressing the developmentally regulated expression and localization of three molecules suggested to be involved in polarized trafficking in kidney epithelia, Rab17, syntaxin 3, and Munc-18-2 [3].
 

Anatomical context of Rab17

References

  1. Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. Hunziker, W., Peters, P.J. J. Biol. Chem. (1998) [Pubmed]
  2. Rab17 and rab18, small GTPases with specificity for polarized epithelial cells: genetic mapping in the mouse. McMurtrie, E.B., Barbosa, M.D., Zerial, M., Kingsmore, S.F. Genomics (1997) [Pubmed]
  3. Vesicular transport and kidney development. Lehtonen, S., Lehtonen, E., Olkkonen, V.M. Int. J. Dev. Biol. (1999) [Pubmed]
 
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