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Gene Review

Stxbp2  -  syntaxin binding protein 2

Mus musculus

Synonyms: C79054, MUSEC1, Munc-18-2, Munc-18b, Munc18-2, ...
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High impact information on Stxbp2


Biological context of Stxbp2


Anatomical context of Stxbp2


Associations of Stxbp2 with chemical compounds

  • With mannitol and sucrose solutions as the medium, a wide range of field strengths (0.31-1.41 kv / cm for 0.26 M sucrose solution and 0.31 to 2.04 kv / cm for 0.3 M mannitol solution) and durations of the electrical pulse (10-1280 musec) resulted in high rates of fusion (often 100%) [10].

Analytical, diagnostic and therapeutic context of Stxbp2


  1. Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner. Fukuda, M., Imai, A., Nashida, T., Shimomura, H. J. Biol. Chem. (2005) [Pubmed]
  2. Munc18-syntaxin complexes and exocytosis in human platelets. Houng, A., Polgar, J., Reed, G.L. J. Biol. Chem. (2003) [Pubmed]
  3. Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes. Tamori, Y., Kawanishi, M., Niki, T., Shinoda, H., Araki, S., Okazawa, H., Kasuga, M. J. Biol. Chem. (1998) [Pubmed]
  4. Electrofusion. A new, highly efficient technique for generating somatic cell hybrids. Finaz, C., Lefevre, A., Teissié, J. Exp. Cell Res. (1984) [Pubmed]
  5. Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development. Lehtonen, S., Riento, K., Olkkonen, V.M., Lehtonen, E. Kidney Int. (1999) [Pubmed]
  6. Molecular characterization of a nonneuronal human UNC18 homolog. Ziegler, S.F., Mortrud, M.T., Swartz, A.R., Baker, E., Sutherland, G.R., Burmeister, M., Mulligan, J.T. Genomics (1996) [Pubmed]
  7. Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. Tellam, J.T., McIntosh, S., James, D.E. J. Biol. Chem. (1995) [Pubmed]
  8. A sec1-related vesicle-transport protein that is expressed predominantly in epithelial cells. Riento, K., Jäntti, J., Jansson, S., Hielm, S., Lehtonen, E., Ehnholm, C., Keränen, S., Olkkonen, V.M. Eur. J. Biochem. (1996) [Pubmed]
  9. Conduction of nervous impulses in spinal roots and peripheral nerves of dystrophic mice. Rasminsky, M., Kearney, R.E., Aguayo, A.J., Bray, G.M. Brain Res. (1978) [Pubmed]
  10. Factors affecting electrofusion of 2-cell mouse embryos. Tan, J.H., Zhou, Q., Xu, L.B., Zhang, Q.M., Qin, P.C. Theriogenology (1994) [Pubmed]
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