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Gene Review

HIPK1  -  homeodomain interacting protein kinase 1

Homo sapiens

Synonyms: Homeodomain-interacting protein kinase 1, KIAA0630, MGC26642, MGC33446, MGC33548, ...
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High impact information on HIPK1


Biological context of HIPK1


Other interactions of HIPK1


  1. Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. Aikawa, Y., Nguyen, L.A., Isono, K., Takakura, N., Tagata, Y., Schmitz, M.L., Koseki, H., Kitabayashi, I. EMBO J. (2006) [Pubmed]
  2. Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop. Song, J.J., Lee, Y.J. J. Cell Biol. (2005) [Pubmed]
  3. PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains. Möller, A., Sirma, H., Hofmann, T.G., Rueffer, S., Klimczak, E., Dröge, W., Will, H., Schmitz, M.L. Cancer Res. (2003) [Pubmed]
  4. Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. Li, X., Zhang, R., Luo, D., Park, S.J., Wang, Q., Kim, Y., Min, W. J. Biol. Chem. (2005) [Pubmed]
  5. Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization. Song, J.J., Lee, Y.J. J. Biol. Chem. (2003) [Pubmed]
  6. DJ-1 interacts with HIPK1 and affects H2O2-induced cell death. Sekito, A., Koide-Yoshida, S., Niki, T., Taira, T., Iguchi-Ariga, S.M., Ariga, H. Free Radic. Res. (2006) [Pubmed]
  7. US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrest. Giraud, S., Diaz-Latoud, C., Hacot, S., Textoris, J., Bourette, R.P., Diaz, J.J. J. Virol. (2004) [Pubmed]
  8. Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability. Gresko, E., Möller, A., Roscic, A., Schmitz, M.L. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
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