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Gene Review

TMCC1  -  transmembrane and coiled-coil domain family 1

Homo sapiens

Synonyms: KIAA0779, Transmembrane and coiled-coil domains protein 1
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Disease relevance of TMCC1

  • TRAP assay is used for telomerase activity, flow cytometry analysis and pKi-67 immunofluoroscein staining in cervical adenocarcinoma cell lines (OMC-4, TMCC-1) [1].
  • BACKGROUND: This study was carried out with the aim of detecting possible differences between proteins secreted by fresh wild isolates of Mycobacterium tuberculosis and from a reference strain of this microorganism, H37Rv TMCC 102 [2].

High impact information on TMCC1


  1. Inhibitory effect of the tea polyphenol, (-)-epigallocatechin gallate, on growth of cervical adenocarcinoma cell lines. Noguchi, M., Yokoyama, M., Watanabe, S., Uchiyama, M., Nakao, Y., Hara, K., Iwasaka, T. Cancer Lett. (2006) [Pubmed]
  2. Secretion antigens of Mycobacterium tuberculosis: a comparison between a reference strain and seven wild isolates. Rojas-Espinosa, O., Rangel-Moreno, J., Amador-Jiménez, A., Parra-Maldonado, R., Arce-Paredes, P., Torres-López, J. Arch. Med. Res. (1999) [Pubmed]
  3. Growth suppression of a cervical cancer cell line (TMCC-1) by the human wild-type p53 gene. Zheng, P.S., Iwasaka, T., Ouchida, M., Fukuda, K., Yokoyama, M., Sugimori, H. Gynecol. Oncol. (1996) [Pubmed]
  4. Cytologic changes in two cervical carcinoma cell lines after transfection of the wild-type p53 gene. Iwasaka, T., Zheng, P.S., Ouchida, M., Yamasaki, H., Yokoyama, M., Sugimori, H. Acta obstetricia et gynecologica Scandinavica. (1996) [Pubmed]
  5. Changes in CA125 release and surface expression caused by drugs in uterine cervix adenocarcinoma cells. Nakai, T., Sakahara, H., Endo, K., Shirato, M., Kobayashi, H., Hosono, M., Saga, T., Sakamoto, M., Konishi, J. Annals of nuclear medicine. (1993) [Pubmed]
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