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Chemical Compound Review

butanoic acid     butanoic acid

Synonyms: butanate, butanoate, Buttersaeure, propylformate, n-Butyric acid, ...
 
 
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Disease relevance of butanoic acid

 

Psychiatry related information on butanoic acid

 

High impact information on butanoic acid

 

Chemical compound and disease context of butanoic acid

 

Biological context of butanoic acid

 

Anatomical context of butanoic acid

 

Associations of butanoic acid with other chemical compounds

 

Gene context of butanoic acid

  • Quantitation of transcripts of CD86 accompanied with RNA synthesis inhibition assay and nuclear run-on assay revealed that SB up-regulates the CD86 expression transcriptionally [31].
  • Treatment of HL-60 eosinophilic sublines with either interleukin-5 or butyric acid increased the expression of GATA-1 mRNA concomitant with the expression of eosinophil-specific genes, whereas levels of GATA-2 mRNA remained relatively constant [32].
  • Butyric acid promoted the synthesis of hemoglobin in UT-7/Epo, but not UT-7 [33].
  • The expression of CD80, CD86, human leukocyte antigen (HLA)-DR, HLA-ABC, and intracellular adhesion molecule-1 (ICAM-1) was tested in human AML cell lines after the addition of HDACI, sodium butyrate (SB) [31].
  • Pretreatment of cells with the JNK inhibitor SP600125 attenuated the effect of butyric acid on apoptosis, whereas no effect was seen with the p38 inhibitor SB202190 or the ERK inhibitor PD98059 [34].
 

Analytical, diagnostic and therapeutic context of butanoic acid

References

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