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Gene Review

Gclm  -  Glutamate-cysteine ligase modifier subunit

Drosophila melanogaster

Synonyms: 4919, CG4919, DmGCLM, DmGCSl, Dmel\CG4919, ...
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Disease relevance of Gclm


High impact information on Gclm


Physical interactions of Gclm

  • DmGCLC co-immunoprecipitated with DmGCLM from S2 cell extracts, suggesting that they also associate in vivo [1].

Analytical, diagnostic and therapeutic context of Gclm

  • This yielded two fully viable and fertile recombinants bearing the P-element insertion, which Western and Northern blotting indicated is a severely hypomorphic allele of Gclm [2].


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