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Gene Review

LCORL  -  ligand dependent nuclear receptor...

Homo sapiens

Synonyms: FLJ30696, LCoR-like protein, Ligand-dependent nuclear receptor corepressor-like protein, MLR1
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Disease relevance of LCORL


High impact information on LCORL


Analytical, diagnostic and therapeutic context of LCORL

  • MLR1 and MLR2 bound to human p75NTR with higher affinity than the well-characterized ME20.4 in ELISA and also recognized p75NTR present on neurons in both rat and mouse [4].


  1. Activated T lymphocytes in patients with multiple sclerosis. Golaz, J., Steck, A., Moretta, L. Neurology (1983) [Pubmed]
  2. Surface antigens specifically expressed by activated T cells in humans. Corte, G., Moretta, L., Damiani, G., Mingari, M.C., Bargellesi, A. Eur. J. Immunol. (1981) [Pubmed]
  3. Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1). Kunieda, T., Park, J.M., Takeuchi, H., Kubo, T. FEBS Lett. (2003) [Pubmed]
  4. Functional monoclonal antibodies to p75 neurotrophin receptor raised in knockout mice. Rogers, M.L., Atmosukarto, I., Berhanu, D.A., Matusica, D., Macardle, P., Rush, R.A. J. Neurosci. Methods (2006) [Pubmed]
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