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Gene Review

ABCA4  -  ATP-binding cassette, sub-family A (ABC1),...

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High impact information on ABCA4


Biological context of ABCA4

  • Our studies further suggest that ATP binding and hydrolysis induces a protein conformational change that causes N-retinylidene-phosphatidylethanolamine to dissociate from ABCA4 [1].

Anatomical context of ABCA4

  • ABCA4, a member of the family of ATP binding cassette (ABC) proteins found in rod and cone photoreceptors, has been implicated in the transport of retinoid compounds across the outer segment disk membrane following the photoactivation of rhodopsin [1].

Associations of ABCA4 with chemical compounds


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