The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

YWHAG  -  tyrosine 3-monooxygenase/tryptophan 5...

Bos taurus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of YWHAG


High impact information on YWHAG


Anatomical context of YWHAG

  • The 110 kDa polypeptide and its fragments were phosphorylated by a nuclear envelope kinase and this phosphorylation was inhibited by a monoclonal antibody against protein kinase C and by a specific protein kinase C inhibitor obtained from bovine brain [7].

Associations of YWHAG with chemical compounds

  • Furthermore, the TPA-induced PLD activation was inhibited not only by the protein kinase C inhibitor, Go6976, but also by the tyrosine kinase inhibitor, genistein, and by the Src kinase specific inhibitor, PP-2, suggesting the involvement of protein kinase C and also tyrosine kinases in TPA-induced PLD activation [8].


  1. 17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide synthase and GTP cyclohydrolase I by high glucose: relevance to postmenopausal diabetic cardiovascular disease. Miyazaki-Akita, A., Hayashi, T., Ding, Q.F., Shiraishi, H., Nomura, T., Hattori, Y., Iguchi, A. J. Pharmacol. Exp. Ther. (2007) [Pubmed]
  2. Tyrosine hydroxylase in bovine adrenal chromaffin cells: angiotensin II-stimulated activity and phosphorylation of Ser19, Ser31, and Ser40. Bobrovskaya, L., Cheah, T.B., Bunn, S.J., Dunkley, P.R. J. Neurochem. (1998) [Pubmed]
  3. Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M1 receptors. Shiraishi, M., Minami, K., Uezono, Y., Yanagihara, N., Shigematsu, A. J. Pharmacol. Exp. Ther. (2001) [Pubmed]
  4. Inhibition of interleukin-1-induced proteoglycan degradation and nitric oxide production in bovine articular cartilage/chondrocyte cultures by the natural product, hymenialdisine. Badger, A.M., Cook, M.N., Swift, B.A., Newman-Tarr, T.M., Gowen, M., Lark, M. J. Pharmacol. Exp. Ther. (1999) [Pubmed]
  5. A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli. Muid, R.E., Dale, M.M., Davis, P.D., Elliott, L.H., Hill, C.H., Kumar, H., Lawton, G., Twomey, B.M., Wadsworth, J., Wilkinson, S.E. FEBS Lett. (1991) [Pubmed]
  6. Ca(2+) signal stimulates the expression of steroidogenic acute regulatory protein and steroidogenesis in bovine adrenal fasciculata-reticularis cells. Yamazaki, T., Kawasaki, H., Takamasa, A., Yoshitomi, T., Kominami, S. Life Sci. (2006) [Pubmed]
  7. Immunological evidence for the localization of a 110 kDa poly(A) binding protein from rat liver in nuclear envelopes and its phosphorylation by protein kinase C. Schäfer, P., Aitken, S.J., Bachmann, M., Agutter, P.S., Müller, W.E., Prochnow, D. Cell. Mol. Biol. (Noisy-le-grand) (1993) [Pubmed]
  8. Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells. Roy, S., Parinandi, N., Zeigelstein, R., Hu, Q., Pei, Y., Travers, J.B., Natarajan, V. Antioxid. Redox Signal. (2003) [Pubmed]
WikiGenes - Universities