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Gene Review

TFCP2L1  -  transcription factor CP2-like 1

Homo sapiens

Synonyms: CP2-related transcriptional repressor 1, CRTR-1, CRTR1, LBP-9, LBP9, ...
 
 
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Disease relevance of TFCP2L1

  • A yeast one-hybrid screen of 2.4 x 10(6) cDNA clones from human placental JEG-3 cells yielded two unique clones; one is the previously described transcription factor LBP-1b, which is induced by HIV, type I infection of lymphocytes, and the other is a new factor, termed LBP-9, that shares 83% amino acid sequence identity with LBP-1b [1].
 

High impact information on TFCP2L1

 

Biological context of TFCP2L1

 

Anatomical context of TFCP2L1

  • All cell lines stably expressing a fusion protein of LBP-1b and enhanced green fluorescent protein increased P450scc expression, but cell lines stably expressing LBP-9 fused to enhanced green fluorescent protein either increased or decreased P450scc expression [2].

References

 
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