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Gene Review

rx3  -  retinal homeobox gene 3

Danio rerio

Synonyms: Retinal homeobox protein Rx3, SO:0000704
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High impact information on rx3


Analytical, diagnostic and therapeutic context of rx3

  • Cellular transplantations demonstrate that rx3 function is autonomously required to specify the prospective RPE [2].


  1. Loss of eyes in zebrafish caused by mutation of chokh/rx3. Loosli, F., Staub, W., Finger-Baier, K.C., Ober, E.A., Verkade, H., Wittbrodt, J., Baier, H. EMBO Rep. (2003) [Pubmed]
  2. chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Rojas-Muñoz, A., Dahm, R., Nüsslein-Volhard, C. Dev. Biol. (2005) [Pubmed]
  3. Zebrafish rx3 and mab21l2 are required during eye morphogenesis. Kennedy, B.N., Stearns, G.W., Smyth, V.A., Ramamurthy, V., van Eeden, F., Ankoudinova, I., Raible, D., Hurley, J.B., Brockerhoff, S.E. Dev. Biol. (2004) [Pubmed]
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