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Gene Review

pSCFS1_03  -  ABC transporter

Staphylococcus sciuri

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Disease relevance of pSCFS1_03


High impact information on pSCFS1_03

  • From a mass-excised Staphylococcus aureus lambdaZapII expression library, we cloned an operon encoding a novel ABC transporter with significant homology to bacterial siderophore transporter systems [1].
  • For further analysis of the ABC transporter, a approximately 3 kb EcoRV-HpaI fragment was cloned into the staphylococcal plasmid pT181MCS and the respective S. aureus RN4220 transformants were subjected to MIC determination [4].
  • Transposon mutagenesis of Staphylococcus carnosus led to the identification of three genes, modABC, which encode an ABC transporter that is involved in molybdate transport [5].
  • A gene (ertX) encoding a putative ABC transporter was cloned from the erythromycin producer Saccharopolyspora erythraea, using PCR [3].


  1. Molecular cloning and analysis of a putative siderophore ABC transporter from Staphylococcus aureus. Morrissey, J.A., Cockayne, A., Hill, P.J., Williams, P. Infect. Immun. (2000) [Pubmed]
  2. Molecular cloning of a 32-kilodalton lipoprotein component of a novel iron-regulated Staphylococcus epidermidis ABC transporter. Cockayne, A., Hill, P.J., Powell, N.B., Bishop, K., Sims, C., Williams, P. Infect. Immun. (1998) [Pubmed]
  3. The use of PCR to isolate a putative ABC transporter from Saccharopolyspora erythraea. O'Neill, M.P., Eady, E.A., Radford, A., Baumberg, S., Cove, J.H. FEMS Microbiol. Lett. (1995) [Pubmed]
  4. Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri. Kehrenberg, C., Ojo, K.K., Schwarz, S. J. Antimicrob. Chemother. (2004) [Pubmed]
  5. Characterization of the molybdate transport system ModABC of Staphylococcus carnosus. Neubauer, H., Pantel, I., Lindgren, P.E., Götz, F. Arch. Microbiol. (1999) [Pubmed]
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