The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Lsp1beta  -  Larval serum protein 1 beta

Drosophila melanogaster

Synonyms: CG4178, DmeLSP1b, Dmel\CG4178, Hexamerin-1-beta, LSP 1, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Lsp1beta

  • Taken together these data indicate that the 1.65 X 10(3) and 2.25 X 10(3) base segments of DNA upstream from the LSP1 alpha and LSP1 beta genes contain cis-acting regulatory elements necessary for correct tissue and temporal specificity of LSP1 gene expression [1].
  • The same chromosomal localization and genomic organization, different from that of D. melanogaster, is found in both species for the Lsp1beta and Lsp1gamma genes [2].
  • To understand the structural and functional differences between these two storage hexamers, the nucleotide sequence of the coding region of the Lsp-1 beta gene was determined for comparison with LSP-2 and a number of other arthropod hexamerins [3].
  • Lsp-1 beta is also more closely related to calliphorin with respect to the protein domain structure, the presence of a single intron in its gene, and the absence of glycosylation sites [3].
  • The Drosophila Lsp-1 beta gene. A structural and phylogenetic analysis [3].

Biological context of Lsp1beta


Anatomical context of Lsp1beta

  • To test its role in male courtship, fat body was feminized using the highly specific Larval serum protein promoter [4].


  1. Expression of the prokaryotic gene for chloramphenicol acetyl transferase in Drosophila under the control of larval serum protein 1 gene promoters. Davies, J.A., Addison, C.F., Delaney, S.J., Sunkel, C., Glover, D.M. J. Mol. Biol. (1986) [Pubmed]
  2. Duplicative and conservative transpositions of larval serum protein 1 genes in the genus Drosophila. González, J., Casals, F., Ruiz, A. Genetics (2004) [Pubmed]
  3. The Drosophila Lsp-1 beta gene. A structural and phylogenetic analysis. Massey, H.C., Kejzlarová-Lepesant, J., Willis, R.L., Castleberry, A.B., Benes, H. Eur. J. Biochem. (1997) [Pubmed]
  4. A role for the adult fat body in Drosophila male courtship behavior. Lazareva, A.A., Roman, G., Mattox, W., Hardin, P.E., Dauwalder, B. PLoS Genet. (2007) [Pubmed]
WikiGenes - Universities