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Gene Review

JUND  -  jun D proto-oncogene

Homo sapiens

Synonyms: AP-1, Transcription factor jun-D
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Disease relevance of JUND


High impact information on JUND


Biological context of JUND


Associations of JUND with chemical compounds

  • Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND [7].


  1. RNA helicase A is necessary for translation of selected messenger RNAs. Hartman, T.R., Qian, S., Bolinger, C., Fernandez, S., Schoenberg, D.R., Boris-Lawrie, K. Nat. Struct. Mol. Biol. (2006) [Pubmed]
  2. Decreased transcription factor junD in brains of patients with Down syndrome. Labudova, O., Krapfenbauer, K., Moenkemann, H., Rink, H., Kitzmüller, E., Cairns, N., Lubec, G. Neurosci. Lett. (1998) [Pubmed]
  3. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Agarwal, S.K., Guru, S.C., Heppner, C., Erdos, M.R., Collins, R.M., Park, S.Y., Saggar, S., Chandrasekharappa, S.C., Collins, F.S., Spiegel, A.M., Marx, S.J., Burns, A.L. Cell (1999) [Pubmed]
  4. Attractive interhelical electrostatic interactions in the proline- and acidic-rich region (PAR) leucine zipper subfamily preclude heterodimerization with other basic leucine zipper subfamilies. Moll, J.R., Olive, M., Vinson, C. J. Biol. Chem. (2000) [Pubmed]
  5. Inhibition of Ret oncogene activity by the protein tyrosine phosphatase SHP1. Hennige, A.M., Lammers, R., Höppner, W., Arlt, D., Strack, V., Teichmann, R., Machicao, F., Ullrich, A., Häring, H.U., Kellerer, M. Endocrinology (2001) [Pubmed]
  6. Gene expression profiling of noninvasive primary urothelial tumours using microarrays. Aaboe, M., Marcussen, N., Jensen, K.M., Thykjaer, T., Dyrskjøt, L., Orntoft, T.F. Br. J. Cancer (2005) [Pubmed]
  7. Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND. Sullivan, M., Olsen, A.S., Houslay, M.D. Cell. Signal. (1999) [Pubmed]
  8. Assignment of rat Jun family genes to chromosome 19 (Junb), chromosome 5q31-33 (Jun), and chromosome 16 (Jund). Szpirer, C., Tissir, F., Rivière, M., Levan, G., Szpirer, J. Mamm. Genome (1994) [Pubmed]
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