Disease relevance of GPC

• Conversely, the CH-specific antisera reacted with the nucleocapsid, GP2, and GPC proteins of LCMV [1].
• These antigens had the same electrophoretic mobilities on sodium dodecyl sulfate-polyacrylamide gels as did the nucleocapsid, GP2, and GPC proteins of lymphocytic choriomeningitis virus (LCMV) [1].
• In view of this, and if, like Pichinde virus, LCM has an ambisense S RNA coding strategy, then it is probable that the intergenic hairpins function as transcription terminators for the N and GPC mRNA species of both viruses [2].
• The expression of the two LCMV S-coded genes, the nucleoprotein and glycoprotein precursor, in S. frugiperda cells by the recombinant baculoviruses is described [3].

High impact information on GPC

• The cells' content of NP was high, but they contained little GP-C; instead, a viral glycoprotein with MW 65,000 was present [4].
• The glycoprotein precursor has a primary amino acid size of 56293 Da and is rich in potential glycosylation sites as well as histidine and cysteine residues [5].

Other interactions of GPC

• Full-length sequences of the NP, GPC, Z and L genes were used to reconstruct phylogenetic relationships and to compare resulting tree topologies [6].

References