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Gene Review

NP  -  nucleocapsid protein

Ippy virus

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Disease relevance of NP


High impact information on NP


Biological context of NP


Anatomical context of NP


Associations of NP with chemical compounds

  • The last-mentioned glycoprotein also appears to be complexed with p63, the main protein component of the nucleocapsid, and this in turn was found to be spatially associated with p200 [14].

Analytical, diagnostic and therapeutic context of NP


  1. Sequence analysis of the S RNA of the African arenavirus Mopeia: an unusual secondary structure feature in the intergenic region. Wilson, S.M., Clegg, J.C. Virology (1991) [Pubmed]
  2. Isolation of an arenavirus from a marmoset with callitrichid hepatitis and its serologic association with disease. Stephensen, C.B., Jacob, J.R., Montali, R.J., Holmes, K.V., Muchmore, E., Compans, R.W., Arms, E.D., Buchmeier, M.J., Lanford, R.E. J. Virol. (1991) [Pubmed]
  3. Biochemical and immunological evidence that the 11 kDa zinc-binding protein of lymphocytic choriomeningitis virus is a structural component of the virus. Salvato, M.S., Schweighofer, K.J., Burns, J., Shimomaye, E.M. Virus Res. (1992) [Pubmed]
  4. Vaccinia recombinant expressing Lassa-virus internal nucleocapsid protein protects guineapigs against Lassa fever. Clegg, J.C., Lloyd, G. Lancet (1987) [Pubmed]
  5. Identification of Lassa fever virus infection with recombinant nucleocapsid protein antigen. Lloyd, G., Barber, G.N., Clegg, J.C., Kelly, P. Lancet (1989) [Pubmed]
  6. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. Lee, K.J., Novella, I.S., Teng, M.N., Oldstone, M.B., de La Torre, J.C. J. Virol. (2000) [Pubmed]
  7. Differential immune recognition of LCMV nucleoprotein and glycoprotein in transgenic mice expressing LCMV cDNA genes. Zeller, J.C., Nguyen, N., Southern, P.J. Virology (1997) [Pubmed]
  8. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Pushko, P., Parker, M., Ludwig, G.V., Davis, N.L., Johnston, R.E., Smith, J.F. Virology (1997) [Pubmed]
  9. Molecular cloning of Lassa virus RNA: nucleotide sequence and expression of the nucleocapsid protein gene. Clegg, J.C., Oram, J.D. Virology (1985) [Pubmed]
  10. A protein kinase activity in lymphocytic choriomeningitis virus and identification of the phosphorylated product using monoclonal antibody. Howard, C.R., Buchmeier, M.J. Virology (1983) [Pubmed]
  11. Expression of the Lassa virus nucleocapsid protein in insect cells infected with a recombinant baculovirus: application to diagnostic assays for Lassa virus infection. Barber, G.N., Clegg, J.C., Lloyd, G. J. Gen. Virol. (1990) [Pubmed]
  12. Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts. Bowen, M.D., Peters, C.J., Nichol, S.T. Mol. Phylogenet. Evol. (1997) [Pubmed]
  13. Identification of messenger RNA for nucleocapsid protein of Lassa virus in infected cells. Lukashevich, I.S., Stelmakh, T.A., Stchesljenok, E.P., Shkolina, T.V. Intervirology (1988) [Pubmed]
  14. Lymphocytic choriomeningitis virus. V. Proposed structural arrangement of proteins in the virion. Bruns, M., Lehmann-Grube, F. J. Gen. Virol. (1983) [Pubmed]
  15. Ultrastructural localization of viral antigens in the CNS of mice persistently infected with lymphocytic choriomeningitis virus (LCMV). Rodriguez, M., Buchmeier, M.J., Oldstone, M.B., Lampert, P.W. Am. J. Pathol. (1983) [Pubmed]
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