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Gene Review:

SOX10 - SRY (sex determining region Y)-box 10

Gallus gallus

O'donnell, M. et al., Cheng, Y. et al., Bell, K.M. et al.

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High impact information on SOX10

Here, we show that in Xenopus, Sox8 accumulates at the lateral edges of the neural plate at the mid-gastrula stage; in contrast to its mouse and chick orthologs, Sox8 expression precedes that of Sox9 and Sox10 in neural crest progenitors [1].
This gene shows a high degree of sequence homology to SOX9 and SOX10 [2].
Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system [3].

References

Functional analysis of Sox8 during neural crest development in Xenopus. O'donnell, M., Hong, C.S., Huang, X., Delnicki, R.J., Saint-Jeannet, J.P. Development (2006) [Pubmed]
SOX8 expression during chick embryogenesis. Bell, K.M., Western, P.S., Sinclair, A.H. Mech. Dev. (2000) [Pubmed]
Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system. Cheng, Y., Cheung, M., Abu-Elmagd, M.M., Orme, A., Scotting, P.J. Brain Res. Dev. Brain Res. (2000) [Pubmed]

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