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Gene Review

CHRD  -  chordin

Gallus gallus

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High impact information on CHRD


Biological context of CHRD

  • The mutual down-regulation of noggin/chordin and BMP-4 is proposed to function as an indirect self-enhancement, establishing in this way an essential prerequisite for primary pattern formation [5].

Anatomical context of CHRD


Analytical, diagnostic and therapeutic context of CHRD

  • As an initial step in addressing this issue, we have investigated by in situ hybridization the expression patterns of BMP-2, -4, -5, -6, and -7, BMP receptor kinases (BRKs) -1, -2, and -3, and BMP binding proteins noggin and chordin, in the chick embryonic eye at embryonic day 3 (E3), and in isolated retinas at E6, E8, and E18 [6].


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