The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CCNA2  -  cyclin A2

Gallus gallus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CCNA2


Biological context of CCNA2

  • These data show that the cell cycle protein cyclin A is induced in fiber-associated cells during the early growth response in loaded ALD but also implicate an activation of interstitial cells as playing an early role in this model for muscle growth [4].

Other interactions of CCNA2


Analytical, diagnostic and therapeutic context of CCNA2

  • Immunoblotting analysis identified that cyclin A protein per total protein was dramatically increased in ALD muscle after 1.5 days of loading but returned to control level at 7 days [4].
  • Immunofluorescence experiments demonstrated that the increase of cyclin A in 1.5 days of loaded ALD was primarily confined to nuclei of interstitial cells (92%) but was also found in fiber-associated cells (8%) [4].


  1. MHC class II and c-kit expression allows rapid enrichment of T-cell progenitors from total bone marrow cells. Ody, C., Corbel, C., Dunon, D., Vainio, O., Imhof, B.A. Blood (2000) [Pubmed]
  2. Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts. Uttamsingh, S., Zong, C.S., Wang, L.H. J. Biol. Chem. (2003) [Pubmed]
  3. c-Jun induces apoptosis of starved BM2 monoblasts by activating cyclin A-CDK2. Vanhara, P., Bryja, V., Horv??th, V., Kozub??k, A., Hampl, A., Smarda, J. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  4. Transient induction of cyclin A in loaded chicken skeletal muscle. Flück, M., Kitzmann, M., Däpp, C., Chiquet, M., Booth, F.W., Fernandez, A. J. Appl. Physiol. (2003) [Pubmed]
WikiGenes - Universities