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CCNA2  -  cyclin A2

Gallus gallus

 
 
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High impact information on CCNA2

 

Biological context of CCNA2

  • These data show that the cell cycle protein cyclin A is induced in fiber-associated cells during the early growth response in loaded ALD but also implicate an activation of interstitial cells as playing an early role in this model for muscle growth [4].
 

Other interactions of CCNA2

 

Analytical, diagnostic and therapeutic context of CCNA2

  • Immunoblotting analysis identified that cyclin A protein per total protein was dramatically increased in ALD muscle after 1.5 days of loading but returned to control level at 7 days [4].
  • Immunofluorescence experiments demonstrated that the increase of cyclin A in 1.5 days of loaded ALD was primarily confined to nuclei of interstitial cells (92%) but was also found in fiber-associated cells (8%) [4].

References

  1. MHC class II and c-kit expression allows rapid enrichment of T-cell progenitors from total bone marrow cells. Ody, C., Corbel, C., Dunon, D., Vainio, O., Imhof, B.A. Blood (2000) [Pubmed]
  2. Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts. Uttamsingh, S., Zong, C.S., Wang, L.H. J. Biol. Chem. (2003) [Pubmed]
  3. c-Jun induces apoptosis of starved BM2 monoblasts by activating cyclin A-CDK2. Vanhara, P., Bryja, V., Horv??th, V., Kozub??k, A., Hampl, A., Smarda, J. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  4. Transient induction of cyclin A in loaded chicken skeletal muscle. Flück, M., Kitzmann, M., Däpp, C., Chiquet, M., Booth, F.W., Fernandez, A. J. Appl. Physiol. (2003) [Pubmed]
 
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