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Gene Review:

ArthMp095 - hypothetical protein

Arabidopsis thaliana

Perrin, R. et al., Sakamoto, W. et al., Sakamoto, W. et al., Lilly, J.W. et al., Busi, M.V. et al., et al.

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High impact information on ArthMp095

One rearrangement resulted in the insertion of the rps3-rpl16 operon downstream of atp9 [1].
Two exoribonucleases act sequentially to process mature 3'-ends of atp9 mRNAs in Arabidopsis mitochondria [2].
This enzyme is however not sufficient to completely process atp9 mRNAs, because with down-regulation of another mitochondrial exoribonuclease, AtmtRNaseII, about half of atp9 transcripts exhibit short 3' nucleotide extensions compared with mature mRNAs [2].
There was <4% sequence colinearity surrounding the watermelon and cucumber atp9 coding regions, and the much smaller watermelon mitochondrial genome possessed no significant amounts of cucumber repetitive DNAs [3].
An unusual mitochondrial atp9-rpl16 cotranscript found in the maternal distorted leaf mutant of Arabidopsis thaliana: implication of GUG as an initiation codon in plant mitochondria [4].

Biological context of ArthMp095

Down-regulation of AtmtPNPase results in the accumulation of pretranscripts of several times the size of mature atp9 mRNAs, indicating that 3' processing of these transcripts is performed mainly exonucleolytically by AtmtPNPase [2].
This open reading frame, designated orf224, is co-transcribed with the atp9 gene [5].
Nuclear-encoded mitochondrial complex I gene expression is restored to normal levels by inhibition of unedited ATP9 transgene expression in Arabidopsis thaliana [6].

References

Altered mitochondrial gene expression in a maternal distorted leaf mutant of Arabidopsis induced by chloroplast mutator. Sakamoto, W., Kondo, H., Murata, M., Motoyoshi, F. Plant Cell (1996) [Pubmed]
Two exoribonucleases act sequentially to process mature 3'-ends of atp9 mRNAs in Arabidopsis mitochondria. Perrin, R., Meyer, E.H., Zaepfel, M., Kim, Y.J., Mache, R., Grienenberger, J.M., Gualberto, J.M., Gagliardi, D. J. Biol. Chem. (2004) [Pubmed]
Small, repetitive DNAs contribute significantly to the expanded mitochondrial genome of cucumber. Lilly, J.W., Havey, M.J. Genetics (2001) [Pubmed]
An unusual mitochondrial atp9-rpl16 cotranscript found in the maternal distorted leaf mutant of Arabidopsis thaliana: implication of GUG as an initiation codon in plant mitochondria. Sakamoto, W., Tan, S.H., Murata, M., Motoyoshi, F. Plant Cell Physiol. (1997) [Pubmed]
Loss of RNA editing of rps1 sequences in Oenothera mitochondria. Mundel, C., Schuster, W. Curr. Genet. (1996) [Pubmed]
Nuclear-encoded mitochondrial complex I gene expression is restored to normal levels by inhibition of unedited ATP9 transgene expression in Arabidopsis thaliana. Busi, M.V., Gómez-Casati, D.F., Perales, M., Araya, A., Zabaleta, E. Plant Physiol. Biochem. (2006) [Pubmed]

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