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Gene Review

CYP4A21  -  cytochrome P450, family 4, subfamily A,...

Sus scrofa

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High impact information on CYP4A21


Biological context of CYP4A21

  • The CYP4A21 gene was investigated and found to be approx. 13 kb in size and split into 12 exons [3].
  • Sequence comparison aiming to elucidate the origin of the unique features of CYP4A21 revealed a region of decreased sequence identity from exon 6 to exon 8, strongly suggesting that gene conversion could have contributed to the evolution of CYP4A21 [3].

Associations of CYP4A21 with chemical compounds


Other interactions of CYP4A21


Analytical, diagnostic and therapeutic context of CYP4A21

  • A new member of the cytochrome P450 (CYP) 4A subfamily (CYP4A21) was recently cloned by PCR from pig liver [Lundell, Hansson, and Wikvall (2001) J. Biol. Chem. 276, 9606-9612] [2].


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