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Gene Review

GHRL  -  ghrelin/obestatin prepropeptide

Canis lupus familiaris

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Disease relevance of GHRL


High impact information on GHRL


  1. A growth hormone secretagogue prevents ischemic-induced mortality independently of the growth hormone pathway in dogs with chronic dilated cardiomyopathy. Shen, Y.T., Lynch, J.J., Hargreaves, R.J., Gould, R.J. J. Pharmacol. Exp. Ther. (2003) [Pubmed]
  2. Radioimmunoassay for hexarelin, a peptidic growth hormone secretagogue, and its pharmacokinetic studies. Roumi, M., Lenaerts, V., Boutignon, F., Wuthrich, P., Deghenghi, R., Bellemare, M., Adam, A., Ong, H. Peptides (1995) [Pubmed]
  3. Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. Jacks, T., Hickey, G., Judith, F., Taylor, J., Chen, H., Krupa, D., Feeney, W., Schoen, W., Ok, D., Fisher, M. J. Endocrinol. (1994) [Pubmed]
  4. Orexigenic effects of a growth hormone secretagogue and nitric oxide in aged rats and dogs: correlation with the hypothalamic expression of some neuropeptidergic/receptorial effectors mediating food intake. Rigamonti, A.E., Bonomo, S.M., Scanniffio, D., Cella, S.G., Müller, E.E. J. Gerontol. A Biol. Sci. Med. Sci. (2006) [Pubmed]
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