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Cardiomyopathy, Dilated

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  1. Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. Colbert, M.C., Hall, D.G., Kimball, T.R., Witt, S.A., Lorenz, J.N., Kirby, M.L., Hewett, T.E., Klevitsky, R., Robbins, J. J. Clin. Invest. (1997) [Pubmed]
  2. Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Lee, Y., Naseem, R.H., Duplomb, L., Park, B.H., Garry, D.J., Richardson, J.A., Schaffer, J.E., Unger, R.H. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  3. Beta-blocker treatment of dilated cardiomyopathy. Beneficial effect of carteolol in mice. Tominaga, M., Matsumori, A., Okada, I., Yamada, T., Kawai, C. Circulation (1991) [Pubmed]
  4. Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Mende, U., Kagen, A., Cohen, A., Aramburu, J., Schoen, F.J., Neer, E.J. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  5. Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure. Yoshimura, M., Yasue, H., Okumura, K., Ogawa, H., Jougasaki, M., Mukoyama, M., Nakao, K., Imura, H. Circulation (1993) [Pubmed]
  6. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Knöll, R., Hoshijima, M., Hoffman, H.M., Person, V., Lorenzen-Schmidt, I., Bang, M.L., Hayashi, T., Shiga, N., Yasukawa, H., Schaper, W., McKenna, W., Yokoyama, M., Schork, N.J., Omens, J.H., McCulloch, A.D., Kimura, A., Gregorio, C.C., Poller, W., Schaper, J., Schultheiss, H.P., Chien, K.R. Cell (2002) [Pubmed]
  7. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Xu, X., Meiler, S.E., Zhong, T.P., Mohideen, M., Crossley, D.A., Burggren, W.W., Fishman, M.C. Nat. Genet. (2002) [Pubmed]
  8. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Li, Y., Huang, T.T., Carlson, E.J., Melov, S., Ursell, P.C., Olson, J.L., Noble, L.J., Yoshimura, M.P., Berger, C., Chan, P.H., Wallace, D.C., Epstein, C.J. Nat. Genet. (1995) [Pubmed]
  9. A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy. Hayashi, M., Imanaka-Yoshida, K., Yoshida, T., Wood, M., Fearns, C., Tatake, R.J., Lee, J.D. Nat. Med. (2006) [Pubmed]
  10. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Brancaccio, M., Fratta, L., Notte, A., Hirsch, E., Poulet, R., Guazzone, S., De Acetis, M., Vecchione, C., Marino, G., Altruda, F., Silengo, L., Tarone, G., Lembo, G. Nat. Med. (2003) [Pubmed]
  11. Dilated cardiomyopathy and impaired cardiac hypertrophic response to angiotensin II in mice lacking FGF-2. Pellieux, C., Foletti, A., Peduto, G., Aubert, J.F., Nussberger, J., Beermann, F., Brunner, H.R., Pedrazzini, T. J. Clin. Invest. (2001) [Pubmed]
  12. Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy. Fu, L.X., Magnusson, Y., Bergh, C.H., Liljeqvist, J.A., Waagstein, F., Hjalmarson, A., Hoebeke, J. J. Clin. Invest. (1993) [Pubmed]
  13. Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group. Waagstein, F., Bristow, M.R., Swedberg, K., Camerini, F., Fowler, M.B., Silver, M.A., Gilbert, E.M., Johnson, M.R., Goss, F.G., Hjalmarson, A. Lancet (1993) [Pubmed]
  14. Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. Zhang, X., Hintze, T.H. Circulation (1998) [Pubmed]
  15. Development of decompensated dilated cardiomyopathy is associated with decreased gene expression and activity of the milrinone-sensitive cAMP phosphodiesterase PDE3A. Smith, C.J., Huang, R., Sun, D., Ricketts, S., Hoegler, C., Ding, J.Z., Moggio, R.A., Hintze, T.H. Circulation (1997) [Pubmed]
  16. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. Sussman, M.A., Welch, S., Walker, A., Klevitsky, R., Hewett, T.E., Price, R.L., Schaefer, E., Yager, K. J. Clin. Invest. (2000) [Pubmed]
  17. Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy. Mogensen, J., Klausen, I.C., Pedersen, A.K., Egeblad, H., Bross, P., Kruse, T.A., Gregersen, N., Hansen, P.S., Baandrup, U., Borglum, A.D. J. Clin. Invest. (1999) [Pubmed]
  18. Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. Yamamoto, S., Yang, G., Zablocki, D., Liu, J., Hong, C., Kim, S.J., Soler, S., Odashima, M., Thaisz, J., Yehia, G., Molina, C.A., Yatani, A., Vatner, D.E., Vatner, S.F., Sadoshima, J. J. Clin. Invest. (2003) [Pubmed]
  19. The X-linked gene G4.5 is responsible for different infantile dilated cardiomyopathies. D'Adamo, P., Fassone, L., Gedeon, A., Janssen, E.A., Bione, S., Bolhuis, P.A., Barth, P.G., Wilson, M., Haan, E., Orstavik, K.H., Patton, M.A., Green, A.J., Zammarchi, E., Donati, M.A., Toniolo, D. Am. J. Hum. Genet. (1997) [Pubmed]
  20. Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice. Sussman, M.A., Welch, S., Cambon, N., Klevitsky, R., Hewett, T.E., Price, R., Witt, S.A., Kimball, T.R. J. Clin. Invest. (1998) [Pubmed]
  21. Angiotensin-converting enzyme inhibition and the progression of congestive cardiomyopathy. Effects on left ventricular and myocyte structure and function. Spinale, F.G., Holzgrefe, H.H., Mukherjee, R., Hird, R.B., Walker, J.D., Arnim-Barker, A., Powell, J.R., Koster, W.H. Circulation (1995) [Pubmed]
  22. Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Franco, F., Thomas, G.D., Giroir, B., Bryant, D., Bullock, M.C., Chwialkowski, M.C., Victor, R.G., Peshock, R.M. Circulation (1999) [Pubmed]
  23. Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure. Studer, R., Reinecke, H., Bilger, J., Eschenhagen, T., Böhm, M., Hasenfuss, G., Just, H., Holtz, J., Drexler, H. Circ. Res. (1994) [Pubmed]
  24. Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy. Joza, N., Oudit, G.Y., Brown, D., Bénit, P., Kassiri, Z., Vahsen, N., Benoit, L., Patel, M.M., Nowikovsky, K., Vassault, A., Backx, P.H., Wada, T., Kroemer, G., Rustin, P., Penninger, J.M. Mol. Cell. Biol. (2005) [Pubmed]
  25. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Braz, J.C., Gregory, K., Pathak, A., Zhao, W., Sahin, B., Klevitsky, R., Kimball, T.F., Lorenz, J.N., Nairn, A.C., Liggett, S.B., Bodi, I., Wang, S., Schwartz, A., Lakatta, E.G., DePaoli-Roach, A.A., Robbins, J., Hewett, T.E., Bibb, J.A., Westfall, M.V., Kranias, E.G., Molkentin, J.D. Nat. Med. (2004) [Pubmed]
  26. Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. Olson, T.M., Michels, V.V., Thibodeau, S.N., Tai, Y.S., Keating, M.T. Science (1998) [Pubmed]
  27. Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy. Maddatu, T.P., Garvey, S.M., Schroeder, D.G., Hampton, T.G., Cox, G.A. Hum. Mol. Genet. (2004) [Pubmed]
  28. Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: a major role for inositol 1,4,5-trisphosphate. Felzen, B., Shilkrut, M., Less, H., Sarapov, I., Maor, G., Coleman, R., Robinson, R.B., Berke, G., Binah, O. Circ. Res. (1998) [Pubmed]
  29. On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. Bergo, M.O., Lieu, H.D., Gavino, B.J., Ambroziak, P., Otto, J.C., Casey, P.J., Walker, Q.M., Young, S.G. J. Biol. Chem. (2004) [Pubmed]
  30. C protein-induced myocarditis and subsequent dilated cardiomyopathy: rescue from death and prevention of dilated cardiomyopathy by chemokine receptor DNA therapy. Matsumoto, Y., Tsukada, Y., Miyakoshi, A., Sakuma, H., Kohyama, K. J. Immunol. (2004) [Pubmed]
  31. Cardiac resynchronization therapy homogenizes myocardial glucose metabolism and perfusion in dilated cardiomyopathy and left bundle branch block. Nowak, B., Sinha, A.M., Schaefer, W.M., Koch, K.C., Kaiser, H.J., Hanrath, P., Buell, U., Stellbrink, C. J. Am. Coll. Cardiol. (2003) [Pubmed]
  32. Dobutamine stress 99mTc-tetrofosmin quantitative gated SPECT predicts improvement of cardiac function after carvedilol treatment in patients with dilated cardiomyopathy. Kasama, S., Toyama, T., Kumakura, H., Takayama, Y., Ichikawa, S., Tange, S., Suzuki, T., Kurabayashi, M. J. Nucl. Med. (2004) [Pubmed]
  33. Phenylephrine stress in the evaluation of patients with congestive cardiomyopathies. Slutsky, R.A. Investigative radiology. (1983) [Pubmed]
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