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Gene Review

mtp  -  microsomal triglyceride transfer protein

Danio rerio

Synonyms: SO:0000704, wu:fd36b01, zgc:111876
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High impact information on mtp

  • A significant pretranslational up-regulation of mtp expression was observed in the anterior intestine after feeding [1].
  • In situ hybridizations showed that zebrafish mtp transcripts were distributed in the yolk syncytial layer during early embryogenesis and in anterior intestine and liver from 48 hr postfertilization onward [1].
  • The nutritional regulation of zebrafish mtp expression observed in the anterior intestine supports the notion that this protein, similar to mammalian MTP large subunit, could be a factor implicated directly or indirectly in large lipid droplets accumulation observed in the fish enterocyte after feeding [1].

Analytical, diagnostic and therapeutic context of mtp

  • Real-time quantitative RT-PCR confirmed the developmental regulation and tissue-specificity of mtp expression [1].


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