The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

cfl1  -  cofilin 1 (non-muscle)

Xenopus (Silurana) tropicalis

Synonyms: cfl, xac1, xac2
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of cfl1


High impact information on cfl1

  • We also found that the ectopic expression of Xlimk1/2 clearly prevented dephosphorylation (activation) of Xenopus cofilin (XAC) during oocyte maturation [3].


  1. Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails. Rosenblatt, J., Agnew, B.J., Abe, H., Bamburg, J.R., Mitchison, T.J. J. Cell Biol. (1997) [Pubmed]
  2. Cofilin mediates ATP depletion-induced endothelial cell actin alterations. Suurna, M.V., Ashworth, S.L., Hosford, M., Sandoval, R.M., Wean, S.E., Shah, B.M., Bamburg, J.R., Molitoris, B.A. Am. J. Physiol. Renal Physiol. (2006) [Pubmed]
  3. Functional involvement of Xenopus LIM kinases in progression of oocyte maturation. Takahashi, T., Koshimizu, U., Abe, H., Obinata, T., Nakamura, T. Dev. Biol. (2001) [Pubmed]
WikiGenes - Universities