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Gene Review

AnxB9  -  Annexin B9

Drosophila melanogaster

Synonyms: ANXB9, Ann, AnnIX, Annexin IX, Annexin-9, ...
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High impact information on AnnIX

  • Ann Warren and Julian Crampton here discuss how transposable elements can be exploited as valuable research tools for the molecular characterization of genomes and as DNA vectors for genome manipulation and the 'creation' of transgenic organisms [1].
  • Here we report the cloning of three cDNAs each encoding annexin IX (ANX IX) isoforms from unfertilized eggs of the silkworm, Bombyx mori [2].
  • Identification of three annexin IX isoforms generated by alternative splicing of the carboxyl-terminal exon in silkworm, Bombyx mori [2].
  • Interestingly, the C-terminal tail in ANXs I, II and V were previously confirmed as a binding region for protein kinase C. Thus generation of the three ANX IX isoforms in the silkworm, that are different from other ANXs, may have a functional significance other than binding to Ca(2+) [2].

Analytical, diagnostic and therapeutic context of AnnIX

  • A RT-PCR analysis indicated that the three isoforms of silkworm ANX IX were specifically expressed in various larval tissues and development stages [2].


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