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Gene Review

ANXA11  -  annexin A11

Bos taurus

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Disease relevance of ANXA11


High impact information on ANXA11


Biological context of ANXA11


Anatomical context of ANXA11


Associations of ANXA11 with chemical compounds

  • The wild type (wt) and mt1 mutant lacking three amino acids from N-terminal bound to annexin XI with phosphatidylserine and Ca2+, whereas mt2, mt3 and mt4 with seven, twelve and eighteen amino acids deleted, respectively, did not bind to annexin XI [4].
  • The peptide fragment of calcyclin, CNBr-3 (residues 1-57), digested with cyanogen bromide completely inhibited the interaction of native calcyclin with annexin XI, while CNBr-1 (residues 83-90) and CNBr-2 (residues 58-82) did not affect the binding [4].

Analytical, diagnostic and therapeutic context of ANXA11


  1. Isoform-specific intracellular vesicle formation by recombinant annexin XI-A in Sf9 cells. Sudo, T., Mamiya, N., Goto, M., Watanabe, Y., Hidaka, H. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
  2. CAP-50, a newly identified annexin, localizes in nuclei of cultured fibroblast 3Y1 cells. Mizutani, A., Usuda, N., Tokumitsu, H., Minami, H., Yasui, K., Kobayashi, R., Hidaka, H. J. Biol. Chem. (1992) [Pubmed]
  3. Alternatively spliced annexin XI transcripts encode proteins that differ near the amino-terminus. Towle, C.A., Weissbach, L., Treadwell, B.V. Biochim. Biophys. Acta (1992) [Pubmed]
  4. Binding site of annexin XI on the calcyclin molecule. Watanabe, M., Ando, Y., Tokumitsu, H., Hidaka, H. Biochem. Biophys. Res. Commun. (1993) [Pubmed]
  5. Identification of a novel mammalian annexin. cDNA cloning, sequence analysis, and ubiquitous expression of the annexin XI gene. Towle, C.A., Treadwell, B.V. J. Biol. Chem. (1992) [Pubmed]
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