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Gene Review:

PHB - prohibitin

Bos taurus

Reusch, R.N., He, W. et al., Sutovsky, P. et al.

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High impact information on PHB

The initial ligation of ubiquitin molecules to sperm mitochondrial membrane proteins, one of which could be prohibitin, occurs during spermatogenesis [1].
Eukaryotic PHB had the same narrow range of chain lengths (120-200 subunits) as PHB in bacterial membranes, and was associated with PolyPi of somewhat greater length (170-220) than the bacterial counterpart (130-170) [2].
A cDNA clone encoding a prohibitin-like protein (Toprh) was isolated from a piroplasm cDNA library of Theileria orientalis and its nucleotide sequence was determined [3].

References

Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos. Sutovsky, P., Moreno, R.D., Ramalho-Santos, J., Dominko, T., Simerly, C., Schatten, G. Biol. Reprod. (2000) [Pubmed]
Poly-beta-hydroxybutyrate/calcium polyphosphate complexes in eukaryotic membranes. Reusch, R.N. Proc. Soc. Exp. Biol. Med. (1989) [Pubmed]
Cloning and characterization of cDNA encoding a prohibitin-like protein from Theileria orientalis. He, W., Ohashi, K., Sugimoto, C., Tsuji, M., Onuma, M. Jpn. J. Vet. Res. (2005) [Pubmed]

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AgaP_AGAP009323	Anopheles gambiae str. PEST
PHB3	Arabidopsis thaliana
PHB4	Arabidopsis thaliana
AGOS_AFR313C	Ashbya gossypii ATCC 10895
phb-1	Caenorhabditis elegans
PHB	Canis lupus familiaris
phb	Danio rerio
l(2)37Cc	Drosophila melanogaster
PHB	Gallus gallus
PHB	Homo sapiens
KLLA0D16302g	Kluyveromyces lactis NRRL Y-1140
PHB	Macaca mulatta
MGG_06004	Magnaporthe oryzae 70-15
Phb	Mus musculus
NCU08946	Neurospora crassa OR74A
Os04g0462900	Oryza sativa Japonica Group
Os02g0580500	Oryza sativa Japonica Group
PHB	Pan troglodytes
Phb	Rattus norvegicus
PHB1	Saccharomyces cerevisiae S288c
phb1	Schizosaccharomyces pombe 972h-
phb	Xenopus (Silurana) tropicalis

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