The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Theileria


High impact information on Theileria


Chemical compound and disease context of Theileria


Biological context of Theileria

  • When T cells become infected by the parasite Theileria parva, they acquire a transformed phenotype and no longer require antigen-specific stimulation or exogenous growth factors [9].
  • Genome analysis of Theileria parva [16].
  • Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralizing epitopes: implications for a vaccine [2].
  • TaCRK3 encodes a novel Theileria annulata protein kinase with motifs characteristic of the family of eukaryotic cyclin dependent kinases: a comparative analysis of its expression with TaCRK2 during the parasite life cycle [17].
  • The cDNA encoding a 23-kDa piroplasm membrane protein (p23) of Theileria sergenti Chitose (C)-type was isolated and its nucleotide sequence was determined [18].

Anatomical context of Theileria


Associations of Theileria with chemical compounds


Gene context of Theileria


Analytical, diagnostic and therapeutic context of Theileria


  1. Theileria annulata sporozoite surface antigen expressed in Escherichia coli elicits neutralizing antibody. Williamson, S., Tait, A., Brown, D., Walker, A., Beck, P., Shiels, B., Fletcher, J., Hall, R. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  2. Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralizing epitopes: implications for a vaccine. Nene, V., Gobright, E., Bishop, R., Morzaria, S., Musoke, A. Infect. Immun. (1999) [Pubmed]
  3. Delivery of the p67 sporozoite antigen of Theileria parva by using recombinant Salmonella dublin: secretion of the product enhances specific antibody responses in cattle. Gentschev, I., Glaser, I., Goebel, W., McKeever, D.J., Musoke, A., Heussler, V.T. Infect. Immun. (1998) [Pubmed]
  4. Metastasis of Theileria annulata macroschizont-infected cells in scid mice is mediated by matrix metalloproteinases. Somerville, R.P., Adamson, R.E., Brown, C.G., Hall, F.R. Parasitology (1998) [Pubmed]
  5. Baculovirus surface display of Theileria parva p67 antigen preserves the conformation of sporozoite-neutralizing epitopes. Kaba, S.A., Hemmes, J.C., van Lent, J.W., Vlak, J.M., Nene, V., Musoke, A.J., van Oers, M.M. Protein Eng. (2003) [Pubmed]
  6. Heterotransplantation of Theileria parva-infected cells to athymic mice. Irvin, A.D., Stagg, D.A., Kanhai, G.K., Brown, C.G. Nature (1975) [Pubmed]
  7. Evidence for the induction of casein kinase II in bovine lymphocytes transformed by the intracellular protozoan parasite Theileria parva. ole-MoiYoi, O.K., Brown, W.C., Iams, K.P., Nayar, A., Tsukamoto, T., Macklin, M.D. EMBO J. (1993) [Pubmed]
  8. The entry of Theileria parva sporozoites into bovine lymphocytes: evidence for MHC class I involvement. Shaw, M.K., Tilney, L.G., Musoke, A.J. J. Cell Biol. (1991) [Pubmed]
  9. Jun NH2-terminal kinase is constitutively activated in T cells transformed by the intracellular parasite Theileria parva. Galley, Y., Hagens, G., Glaser, I., Davis, W., Eichhorn, M., Dobbelaere, D. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  10. A recombinant sporozoite surface antigen of Theileria parva induces protection in cattle. Musoke, A., Morzaria, S., Nkonge, C., Jones, E., Nene, V. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  11. Comparative studies of the efficacy of parvaquone and parvaquone-plus-frusemide in the treatment of Theileria parva infection (East Coast fever) in cattle. Mbwambo, H.A., Sudi, F.F., Mkonyi, P.A., Mfinanga, J.M., Mella, E.S., Ngovi, C.J. Vet. Parasitol. (2002) [Pubmed]
  12. Chemotherapy of field cases of East Coast fever using halofuginone lactate. Mbwambo, H.A., Mkonyi, P.A., Sondi, J., Lekaki, K.A. Acta Trop. (1986) [Pubmed]
  13. Field evaluation of parvaquone against naturally occurring East Coast fever. Mbwambo, H.A., Mkonyi, P.A., Chua, R.B. Vet. Parasitol. (1987) [Pubmed]
  14. Clinical efficacy and plasma concentrations of two formulations of buparvaquone in cattle infected with East Coast fever (Theileria parva infection). Muraguri, G.R., Ngumi, P.N., Wesonga, D., Ndungu, S.G., Wanjohi, J.M., Bang, K., Fox, A., Dunne, J., McHardy, N. Res. Vet. Sci. (2006) [Pubmed]
  15. Treatment of theileriosis in crossbred cattle in the Punjab. Singh, J., Gill, J.S., Kwatra, M.S., Sharma, K.K. Tropical animal health and production. (1993) [Pubmed]
  16. Genome analysis of Theileria parva. Morzaria, S.P., Young, J.R. Parasitol. Today (Regul. Ed.) (1993) [Pubmed]
  17. TaCRK3 encodes a novel Theileria annulata protein kinase with motifs characteristic of the family of eukaryotic cyclin dependent kinases: a comparative analysis of its expression with TaCRK2 during the parasite life cycle. Kinnaird, J., Logan, M., Tait, A., Langsley, G. Gene (2001) [Pubmed]
  18. Molecular cloning and characterisation of 23-kDa piroplasm surface proteins of Theileria sergenti and Theileria buffeli. Sako, Y., Asada, M., Kubota, S., Sugimoto, C., Onuma, M. Int. J. Parasitol. (1999) [Pubmed]
  19. IL-2 can enhance the cyclosporin A-mediated inhibition of Theileria parva-infected T cell proliferation. Eichhorn, M., Magnuson, N.S., Reeves, R., Williams, R.O., Dobbelaere, D.A. J. Immunol. (1990) [Pubmed]
  20. Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasite Theileria parva and restricted by products of the major histocompatibility complex. Goddeeris, B.M., Morrison, W.I., Teale, A.J. Eur. J. Immunol. (1986) [Pubmed]
  21. Parasite strain specificity of precursor cytotoxic T cells in individual animals correlates with cross-protection in cattle challenged with Theileria parva. Taracha, E.L., Goddeeris, B.M., Morzaria, S.P., Morrison, W.I. Infect. Immun. (1995) [Pubmed]
  22. Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen. Ballingall, K.T., Luyai, A., Rowlands, G.J., Sales, J., Musoke, A.J., Morzaria, S.P., McKeever, D.J. Infect. Immun. (2004) [Pubmed]
  23. Characterization of a bovine leucocyte differentiation antigen of 145,000 MW restricted to B lymphocytes. Naessens, J., Newson, J., McHugh, N., Howard, C.J., Parsons, K., Jones, B. Immunology (1990) [Pubmed]
  24. Protein analysis of Theileria sergenti/buffeli/orientalis piroplasms by two-dimensional polyacrylamide gel electrophoresis. Sugimoto, C., Kawazu, S., Kamio, T., Fujisaki, K. Parasitology (1991) [Pubmed]
  25. Chemoprophylaxis with tetracycline drugs in the immunisation of cattle against Theileria annulata infection. Gill, B.S., Bhattacharyulu, Y., Kaur, D., Singh, A. Int. J. Parasitol. (1978) [Pubmed]
  26. Characterisation of a glutamine- and proline-rich protein (QP protein) from Theileria parva. Baylis, H.A., Allsopp, B.A., Hall, R., Carrington, M. Mol. Biochem. Parasitol. (1993) [Pubmed]
  27. Transmission of Theileria parva by a population of Rhipicephalus appendiculatus under simulated natural conditions. Young, A.S., Leitch, B.L., Dolan, T.T., Newson, R.M., Ngumi, P.N., Omwoyo, P.L. Parasitology (1983) [Pubmed]
  28. Activity of buparvaquone against Theileria cervi in white-tailed deer. Mitema, E.S., Kocan, A.A., Mukolwe, S.W., Sangiah, S., Sherban, D. Vet. Parasitol. (1991) [Pubmed]
  29. Detection of a novel parasite kinase activity at the Toxoplasma gondii parasitophorous vacuole membrane capable of phosphorylating host IkappaBalpha. Molestina, R.E., Sinai, A.P. Cell. Microbiol. (2005) [Pubmed]
  30. Effect of buparvaquone on the expression of interleukin 2 receptors in Theileria annulata-infected cells. Ahmed, J.S., Rintelen, M., Schein, E., Williams, R.O., Dobbelaere, D. Parasitol. Res. (1992) [Pubmed]
  31. Cloning and characterization of the casein kinase II alpha subunit gene from the lymphocyte-transforming intracellular protozoan parasite Theileria parva. ole-MoiYoi, O.K., Sugimoto, C., Conrad, P.A., Macklin, M.D. Biochemistry (1992) [Pubmed]
  32. Infection with Theileria annulata induces expression of matrix metalloproteinase 9 and transcription factor AP-1 in bovine leucocytes. Baylis, H.A., Megson, A., Hall, R. Mol. Biochem. Parasitol. (1995) [Pubmed]
  33. Characterization of a polymorphic Theileria annulata surface protein (TaSP) closely related to PIM of Theileria parva: implications for use in diagnostic tests and subunit vaccines. Schnittger, L., Katzer, F., Biermann, R., Shayan, P., Boguslawski, K., McKellar, S., Beyer, D., Shiels, B.R., Ahmed, J.S. Mol. Biochem. Parasitol. (2002) [Pubmed]
  34. Cloning and characterization of a 150 kDa microsphere antigen of Theileria parva that is immunologically cross-reactive with the polymorphic immunodominant molecule (PIM). Skilton, R.A., Bishop, R.P., Wells, C.W., Spooner, P.R., Gobright, E., Nkonge, C., Musoke, A.J., Macklin, M., Iams, K.P. Parasitology (1998) [Pubmed]
  35. Infection of mammalian cells with Theileria species. Stagg, D.A., Young, A.S., Leitch, B.L., Grootenhuis, J.G., Dolan, T.T. Parasitology (1983) [Pubmed]
  36. Chemotherapy of Theileria annulata infection with buparvaquone. Dhar, S., Malhotra, D.V., Bhushan, C., Gautam, O.P. Vet. Rec. (1986) [Pubmed]
  37. Detection of the protozoan parasite Theileria annulata in Hyalomma ticks by the polymerase chain reaction. de Kok, J.B., d'Oliveira, C., Jongejan, F. Exp. Appl. Acarol. (1993) [Pubmed]
WikiGenes - Universities