High impact information on PECR

• At low concentrations, TERP stimulates ERalpha transcriptional activity in transient transfection assays [1].
• A dimerization mutant of TERP, TERP L509R, stimulated ERalpha transcription at all concentrations [1].
• These results indicate that we have sequenced the complete terp operon [2].
• Mutation of ERE1 site completely abolishes the estradiol-dependent transcription, indicating that ERE1 site is sufficient to confer estrogen responsiveness to TERP promoter [3].
• EMSAs showed that a single Pit-1 DNA binding element in the vicinity of the TATA box is sufficient to confer response by the TERP promoter [3].

Anatomical context of PECR

• TERP promoter constructs were highly active in MMQ cells, a pure lactotrope cell line, whereas a low basal activity was detected in alphaT3-1 gonadotrope cells or in COS-7 monkey kidney cells [3].

Associations of PECR with chemical compounds

• Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation [4].
• Transient transfection studies, EMSAs, and gel shifts demonstrated that estrogen activates the TERP promoter via an estrogen-responsive element (ERE1) located within the proximal region [3].

Analytical, diagnostic and therapeutic context of PECR

• CONCLUSIONS: Prolonged intra- and extraperitoneal CO2 insufflation for TERP resulted in significant, but mostly clinically unimportant, hemodynamic alterations [5].
• METHODS: For this study, 20 patients were assigned to receive totally endoscopic robot-assisted radical prostatectomy (TERP) via the intra- or extraperitoneal approach [5].
• Thirty-nine patients who were admitted to a midwestern hospital with a coronary problem and who were candidates for cardiac rehabilitation completed the Patient Entrance Into a Cardiac Rehabilitation Program (PECRP) questionnaire [6].

References