Chemical Compound Review:
Phytol (E,7R,11R)-3,7,11,15- tetramethylhexadec-2...
Synonyms:
trans-Phytol, Phytol, E-, CCRIS 8226, CHEMBL1644111, CHEBI:17327, ...
- The Arabidopsis vitamin E pathway gene5-1 mutant reveals a critical role for phytol kinase in seed tocopherol biosynthesis. Valentin, H.E., Lincoln, K., Moshiri, F., Jensen, P.K., Qi, Q., Venkatesh, T.V., Karunanandaa, B., Baszis, S.R., Norris, S.R., Savidge, B., Gruys, K.J., Last, R.L. Plant Cell (2006)
- A reaction center-light-harvesting 1 complex (RC-LH1) from a Rhodospirillum rubrum mutant with altered esterifying pigments: characterization by optical spectroscopy and cryo-electron microscopy. Qian, P., Addlesee, H.A., Ruban, A.V., Wang, P., Bullough, P.A., Hunter, C.N. J. Biol. Chem. (2003)
- Assay for Sjögren-Larsson syndrome based on a deficiency of phytol degradation. van den Brink, D.M., van Miert, J.M., Wanders, R.J. Clin. Chem. (2005)
- Rhodospirillum rubrum possesses a variant of the bchP gene, encoding geranylgeranyl-bacteriopheophytin reductase. Addlesee, H.A., Hunter, C.N. J. Bacteriol. (2002)
- Isoprenoid biosynthesis in the diatoms Rhizosolenia setigera (Brightwell) and Haslea ostrearia (Simonsen). Massé, G., Belt, S.T., Rowland, S.J., Rohmer, M. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate. Tsuchiya, T., Ohta, H., Okawa, K., Iwamatsu, A., Shimada, H., Masuda, T., Takamiya, K. Proc. Natl. Acad. Sci. U.S.A. (1999)
- A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids. Savolainen, K., Kotti, T.J., Schmitz, W., Savolainen, T.I., Sormunen, R.T., Ilves, M., Vainio, S.J., Conzelmann, E., Hiltunen, J.K. Hum. Mol. Genet. (2004)
- Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands. Elmazar, M.M., Nau, H. Arch. Toxicol. (2004)
- Purification and properties of chlorophyllase from greened rye seedlings. Tanaka, K., Kakuno, T., Yamashita, J., Horio, T. J. Biochem. (1982)
- A salvage pathway for phytol metabolism in Arabidopsis. Ischebeck, T., Zbierzak, A.M., Kanwischer, M., Dörmann, P. J. Biol. Chem. (2006)
- Human Dolichol Kinase, a Polytopic Endoplasmic Reticulum Membrane Protein with a Cytoplasmically Oriented CTP-binding Site. Shridas, P., Waechter, C.J. J. Biol. Chem. (2006)
- Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice. Atshaves, B.P., Payne, H.R., McIntosh, A.L., Tichy, S.E., Russell, D., Kier, A.B., Schroeder, F. J. Lipid Res. (2004)
- Characterization of the final step in the conversion of phytol into phytanic acid. van den Brink, D.M., van Miert, J.N., Dacremont, G., Rontani, J.F., Wanders, R.J. J. Biol. Chem. (2005)
- Tocopherol analogs suppress arachidonic acid metabolism via phospholipase inhibition. Pentland, A.P., Morrison, A.R., Jacobs, S.C., Hruza, L.L., Hebert, J.S., Packer, L. J. Biol. Chem. (1992)
- Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein. Wolfrum, C., Ellinghaus, P., Fobker, M., Seedorf, U., Assmann, G., Börchers, T., Spener, F. J. Lipid Res. (1999)
- Metabolism of phytol to phytanic acid in the mouse, and the role of PPAR{alpha} in its regulation. Gloerich, J., van den Brink, D.M., Ruiter, J.P., van Vlies, N., Vaz, F.M., Wanders, R.J., Ferdinandusse, S. J. Lipid Res. (2007)
- Inhibition of Ca2+-induced cytosolic enzyme efflux from skeletal muscle by vitamin E and related compounds. Phoenix, J., Edwards, R.H., Jackson, M.J. Biochem. J. (1989)
- Molecular genetic analysis of terminal steps in bacteriochlorophyll a biosynthesis: characterization of a Rhodobacter capsulatus strain that synthesizes geranylgeraniol-esterified bacteriochlorophyll a. Bollivar, D.W., Wang, S., Allen, J.P., Bauer, C.E. Biochemistry (1994)
- Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. Disch, A., Schwender, J., Müller, C., Lichtenthaler, H.K., Rohmer, M. Biochem. J. (1998)
- Polyunsaturated fats attenuate the dietary phytol-induced increase in hepatic fatty acid oxidation in mice. Hashimoto, T., Shimizu, N., Kimura, T., Takahashi, Y., Ide, T. J. Nutr. (2006)
- Increases in mouse uterine heat shock protein levels are a sensitive and specific response to uterotrophic agents. Papaconstantinou, A.D., Fisher, B.R., Umbreit, T.H., Brown, K.M. Environ. Health Perspect. (2002)
- A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARalpha-dependent and -independent pathways. Gloerich, J., van Vlies, N., Jansen, G.A., Denis, S., Ruiter, J.P., van Werkhoven, M.A., Duran, M., Vaz, F.M., Wanders, R.J., Ferdinandusse, S. J. Lipid Res. (2005)
- Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation. Gloerich, J., Ruiter, J.P., van den Brink, D.M., Ofman, R., Ferdinandusse, S., Wanders, R.J. FEBS Lett. (2006)
- Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes. Goto, T., Takahashi, N., Kato, S., Egawa, K., Ebisu, S., Moriyama, T., Fushiki, T., Kawada, T. Biochem. Biophys. Res. Commun. (2005)
- Identification of fatty aldehyde dehydrogenase in the breakdown of phytol to phytanic acid. van den Brink, D.M., van Miert, J.N., Dacremont, G., Rontani, J.F., Jansen, G.A., Wanders, R.J. Mol. Genet. Metab. (2004)
- Are syn-ligated (bacterio)chlorophyll dimers energetic traps in light-harvesting systems? Balaban, T.S. FEBS Lett. (2003)
- Synthesis and analysis of phytyl and phytenoyl wax esters. Gellerman, J.L., Anderson, W.H., Schlenk, H. Lipids (1975)
- Phytol is a novel tumor promoter on ICR mouse skin. Kagoura, M., Matsui, C., Morohashi, M. Jpn. J. Cancer Res. (1999)
- A novel assay for the prenatal diagnosis of Sjögren-Larsson syndrome. van den Brink, D.M., van Miert, J.M., Wanders, R.J. J. Inherit. Metab. Dis. (2005)
- Antimicrobial terpenoids from Pterocarpus indicus. Ragasa, C.Y., De Luna, R.D., Hofilena, J.G. Nat. Prod. Res. (2005)