Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

PTS-P1 - 6-pyruvoyltetrahydropterin synthase...

Homo sapiens

Xue, F. et al., Jiang, Z. et al., Kluge, C. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of PTS-P1

CONCLUSION: PTRA, PTSP, and RABG were equally efficacious for control of renovascular hypertension [1].
MATERIALS AND METHODS: Medical records and angiograms of 130 patients who underwent PTRA, PTSP, or RABG were retrospectively studied to determine success and complication rates, angiographic stenoses, blood pressures, antihypertensive medications, and serum creatinine levels [1].

High impact information on PTS-P1

The initial treatment cost for bypass grafting was substantially higher than that for PTRA and PTSP of renal arteries [1].
PTS-P1 has 74% similarity to the 3' portion of PTPS cDNA [2].

Biological context of PTS-P1

We used the previously isolated PTPS cDNA as a probe and identified the human gene, PTS, located on chromosome 11q22.3-q23.3, and a retropseudogene, PTS-P1, assigned to 9p12-p13 (symbols approved by the human genome nomenclature committee) [2].

Analytical, diagnostic and therapeutic context of PTS-P1

PURPOSE: To compare the outcomes and costs of percutaneous transluminal renal angioplasty (PTRA), percutaneous transluminal stent placement (PTSP) of renal arteries, and renal arterial bypass grafting (RABG) in treatment of renovascular hypertension [1].
The difference in the total effective rate between the two groups was not statistically significant (P > 0.05), suggesting that electroacupuncture at Huatuojiaji (Extra) is a better therapy for PTSP [3].
The authors have treated 30 cases of postapoplectic thalamic spontaneous pain (PTSP) by electro-acupuncture at Huatuojiaji points (Extra), with the other 30 cases of PTSP treated by oral administration of carbamazepine as the controls [3].

References

Outcome and cost comparison of percutaneous transluminal renal angioplasty, renal arterial stent placement, and renal arterial bypass grafting. Xue, F., Bettmann, M.A., Langdon, D.R., Wivell, W.A. Radiology. (1999) [Pubmed]
Chromosomal localization, genomic structure and characterization of the human gene and a retropseudogene for 6-pyruvoyltetrahydropterin synthase. Kluge, C., Brecevic, L., Heizmann, C.W., Blau, N., Thöny, B. Eur. J. Biochem. (1996) [Pubmed]
Treatment of postapoplectic thalamic spontaneous pain by electroacupuncture at huatuojiaji points. Jiang, Z., Li, C., Li, Y. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.