Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

psen2 - presenilin 2

Danio rerio

Synonyms: PS-2, Pre2, Presenilin-2, SO:0000704, Zf-PS2, ...

Nornes, S. et al., Groth, C. et al.

Groth, Nornes, McCarty, Tamme, Lardelli,

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Psychiatry related information on psen2

Dominant mutations in presenilin1 (PS1) and presenilin2 (PS2) are a major cause of early-onset Alzheimer's disease [1].
We examine the codependency of Psen1 and Psen2 expression during early embryogenesis [1].

High impact information on psen2

In this report we analyze the expression of the zebrafish presenilin1 (Psen1) and presenilin2 (Psen2) proteins during embryogenesis [1].
Identification of a second presenilin gene in zebrafish with similarity to the human Alzheimer's disease gene presenilin2 [2].

References

Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos. Nornes, S., Groth, C., Camp, E., Ey, P., Lardelli, M. Exp. Cell Res. (2003) [Pubmed]
Identification of a second presenilin gene in zebrafish with similarity to the human Alzheimer's disease gene presenilin2. Groth, C., Nornes, S., McCarty, R., Tamme, R., Lardelli, M. Dev. Genes Evol. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP002957	Anopheles gambiae str. PEST
PSEN2	Bos taurus
PSEN2	Canis lupus familiaris
Psn	Drosophila melanogaster
PSEN2	Gallus gallus
PSEN2	Homo sapiens
PSEN2	Macaca mulatta
Psen2	Mus musculus
Os01g0276400	Oryza sativa Japonica Group
PSEN2	Pan troglodytes
Psen2	Rattus norvegicus
psen2	Xenopus (Silurana) tropicalis

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