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MeSH Review

Codependency (Psychology)

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Psychiatry related information on Codependency (Psychology)

  • Our data suggest that genetic 5-HT impairment is not involved in the pathogenesis of heroin addiction or codependence per se, and is probably linked to the presence of familial depression in comorbidity with the addictive disorder [1].

High impact information on Codependency (Psychology)

  • We examined the biochemical consequences of BCR ligation in mouse B cells lacking either Lyn or CD19 for evidence of interaction or codependence [2].
  • We examine the codependency of Psen1 and Psen2 expression during early embryogenesis [3].
  • Multiple regression analysis confirmed a codependence of female BMD on fat and lean masses, whereas male BMD was related only to lean mass [4].
  • Despite reported differences in maximal levels and timing of mCry1, mPer1, and mPer2 RNAs, the corresponding protein levels peaked simultaneously during late day, suggesting a codependency for their stabilization and/or nuclear entry [5].
  • The discordant results of this growth factor combination in these two models may imply codependence of the hematopoietic response to TPO and/or GM-CSF on other factors or cytokines [6].

Chemical compound and disease context of Codependency (Psychology)

  • Participants completed a demographic questionnaire, the Friel Codependency Assessment Inventory, and the Personal Authority in the Family System (PAFS) Questionnaire [7].
  • This ouabain-insensitive K secretion exhibited a codependence on Cl secretion [8].

Gene context of Codependency (Psychology)

  • Codependency. Part I: Origins, characteristics [9].
  • The Holyoake Codependency Index (HCI; G. E. Dear & C. M. Roberts, 2000) is a 13-item self-report measure of codependent traits that has previously shown adequate to high reliability, initial evidence of construct validity, and an internal structure that is consistent across samples [10].
  • Tools of recovery include involvement in a 12 Step program, connecting with other recovering people, daily affirmations and meditations, and attending programs and workshops on codependence [11].


  1. Serotonergic function in mothers of opioid addicts: correlation with comorbid depression. Gerra, G., Caccavari, R., Zaimovic, A., Palladino, M., Chittolini, B., Giucastro, G., Maestri, D., Monica, C., Fertonani-Affini, G., Delsignore, R., Brambilla, F. Acta psychiatrica Scandinavica. (1997) [Pubmed]
  2. The activation and subsequent regulatory roles of Lyn and CD19 after B cell receptor ligation are independent. Xu, Y., Beavitt, S.J., Harder, K.W., Hibbs, M.L., Tarlinton, D.M. J. Immunol. (2002) [Pubmed]
  3. Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos. Nornes, S., Groth, C., Camp, E., Ey, P., Lardelli, M. Exp. Cell Res. (2003) [Pubmed]
  4. Fat mass is an important determinant of whole body bone density in premenopausal women but not in men. Reid, I.R., Plank, L.D., Evans, M.C. J. Clin. Endocrinol. Metab. (1992) [Pubmed]
  5. Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Jilg, A., Moek, J., Weaver, D.R., Korf, H.W., Stehle, J.H., von Gall, C. Eur. J. Neurosci. (2005) [Pubmed]
  6. Lack of efficacy of thrombopoietin and granulocyte-macrophage colony-stimulating factor after total body irradiation and autologous bone marrow transplantation in Rhesus monkeys. Hartong, S.C., Neelis, K.J., Visser, T.P., Wagemaker, G. Exp. Hematol. (2000) [Pubmed]
  7. Family of origin and current relationship influences on codependency. Prest, L.A., Benson, M.J., Protinsky, H.O. Family process. (1998) [Pubmed]
  8. Potassium secretion by the cortical collecting tubule: effect of C1 gradients and ouabain. Wingo, C.S. Am. J. Physiol. (1989) [Pubmed]
  9. Codependency. Part I: Origins, characteristics. Arnold, L.J. AORN journal. (1990) [Pubmed]
  10. Validation of the holyoake codependency index. Dear, G.E., Roberts, C.M. The Journal of psychology. (2005) [Pubmed]
  11. A personal recovery program for codependent nurse practitioners. Adams, C.E., Bayne, T. The Nurse practitioner. (1992) [Pubmed]
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