Gene Review:
Arhgef1 - Rho guanine nucleotide exchange factor...
Rattus norvegicus
Synonyms:
Lbc's second cousin, Lsc, Rho guanine nucleotide exchange factor 1
- The Rho guanine nucleotide exchange factor Lsc homo-oligomerizes and is negatively regulated through domains in its carboxyl terminus that are absent in novel splenic isoforms. Eisenhaure, T.M., Francis, S.A., Willison, L.D., Coughlin, S.R., Lerner, D.J. J. Biol. Chem. (2003)
- Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells. Ying, Z., Jin, L., Palmer, T., Webb, R.C. Mol. Pharmacol. (2006)
- Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats. Jin, L., Ying, Z., Hilgers, R.H., Yin, J., Zhao, X., Imig, J.D., Webb, R.C. J. Pharmacol. Exp. Ther. (2006)
- Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. Ma, X.M., Huang, J., Wang, Y., Eipper, B.A., Mains, R.E. J. Neurosci. (2003)