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Gene Review

RP6  -  retinitis pigmentosa 6 (X-linked recessive)

Homo sapiens

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High impact information on RP6

  • We recently reported the localization of a gene for late-onset autosomal dominant retinitis pigmentosa (adRP; RP6), on the short arm of chromosome 6, by linkage analysis in a large family of Irish origin [1].
  • Nucleotide sequence of a rice (Oryza sativa) prolamin storage protein gene, RP6 [2].
  • Re-use of disposable haemodialysers, cleaned and disinfected with sodium hypochlorite and benzoic acid, was evaluated bacteriologically and clinically during the course of 514 dialysis treatments, performed with 206 RP6 dialysers used up to three times [3].
  • BACKGROUND: The introduction of the RP6 (InTouch Health, Santa Barbara, CA, USA) remote-presence "robot" appears to offer a useful telemedicine device [4].

Analytical, diagnostic and therapeutic context of RP6

  • Two PstI ribotypes were found in MDR/SGI1 isolates, RP1 (n = 38) and RP6 (n = 1) [5].
  • Micro-organisms originating from the dialysate compartment invaded the blood compartment of ' Rhodial RP6 ' haemodialysers in 16 out of 639 dialyses investigated (2.5 per cent) [6].
  • In different dialysis strategies (hemodialysis with Gambro 1.5 m2, RP6 1 m2, Vita 2 1.2 m2), sequential ultrafiltration with RP 6 (1 hour ultrafiltration followed by 3 hours of hemodialysis and hemoperfusion with Absorba 300 C) serum chromatographic pattern and medium size molecules were studied with Sephadex G 15 chromatography [7].
  • Sensitometric effects of varying the intensifying screens used with Agfa Dentus ST8G and RP6 panoramic radiographic films [8].
  • In a third study using the Rhodial 75 system and RP6 dialyser in a group of non-fluid-overloaded patients the separation in time of ultrafiltration from haemodialysis has shown no obvious advantages over regular haemodialysis [9].


  1. Autosomal dominant retinitis pigmentosa (adRP; RP6): cosegregation of RP6 and the peripherin-RDS locus in a late-onset family of Irish origin. Jordan, S.A., Farrar, G.J., Kumar-Singh, R., Kenna, P., Humphries, M.M., Allamand, V., Sharp, E.M., Humphries, P. Am. J. Hum. Genet. (1992) [Pubmed]
  2. Nucleotide sequence of a rice (Oryza sativa) prolamin storage protein gene, RP6. Wen, T.N., Shyur, L.F., Su, J.C., Chen, C.S. Plant Physiol. (1993) [Pubmed]
  3. A clinical and bacteriological evaluation of a re-use system for disposable haemodialysers. Kolmos, H.J. J. Hosp. Infect. (1983) [Pubmed]
  4. Deployment and early experience with remote-presence patient care in a community hospital. Petelin, J.B., Nelson, M.E., Goodman, J. Surgical endoscopy (2007) [Pubmed]
  5. Multiple-antibiotic resistance in Salmonella enterica serotype Paratyphi B isolates collected in France between 2000 and 2003 is due mainly to strains harboring Salmonella genomic islands 1, 1-B, and 1-C. Weill, F.X., Fabre, L., Grandry, B., Grimont, P.A., Casin, I. Antimicrob. Agents Chemother. (2005) [Pubmed]
  6. Bacterial contamination of the blood compartment originating from the dialysate in haemodialysers. Kolmos, H.J. J. Hosp. Infect. (1984) [Pubmed]
  7. Serum chromatographic pattern in different dialysis strategies. Ringoir, S., De Smet, R. The International journal of artificial organs. (1978) [Pubmed]
  8. Sensitometric effects of varying the intensifying screens used with Agfa Dentus ST8G and RP6 panoramic radiographic films. Wakoh, M., Farman, A.G., Scarfe, W.C., Kitagawa, H., Kuroyanagi, K. Dento maxillo facial radiology. (1997) [Pubmed]
  9. Separation of dialysis and ultrafiltration-does it really help? Jones, E.O., Ward, M.K., Hoenich, N.A., Kerr, D.N. Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association. (1977) [Pubmed]
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