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MeSH Review


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Disease relevance of Hemoperfusion


Psychiatry related information on Hemoperfusion


High impact information on Hemoperfusion


Chemical compound and disease context of Hemoperfusion


Biological context of Hemoperfusion


Anatomical context of Hemoperfusion


Associations of Hemoperfusion with chemical compounds


Gene context of Hemoperfusion

  • Morphology of hDAF (CD55) transgenic pig kidneys following ex-vivo hemoperfusion with human blood [30].
  • In vitro PMX-F hemoperfusion studies have demonstrated effective ET removal, using either the Limulus amebocyte lysate assay or TNF alpha production by peripheral blood mononuclear cells (PBMC) as an index of ET removal [31].
  • A number of other intriguing reagents, including anti-TNF-alpha antibody preparations, IL-1ra, bacterial permeability-increasing protein, TNF-binding protein, polymyxin B hemoperfusion, and lipid A analogues also are undergoing experimental and clinical testing in an attempt to reduce the mortality of this lethal disease process [32].
  • Although reports exist on the use of MARS (molecular adsorbents recirculating system) dialysis, peritoneal dialysis, and standard dialysis for the elimination, in practice, hemoperfusion, is the most often applied technique [33].
  • Ex-vivo hemoperfusion (eHPS) of pig-lungs with whole human blood: effects of complement inhibition with a soluble C1-esterase-inhibitor [34].

Analytical, diagnostic and therapeutic context of Hemoperfusion


  1. Digoxin overdose. Limitations of hemoperfusion-hemodialysis treatment. Warren, S.E., Fanestil, D.D. JAMA (1979) [Pubmed]
  2. Predictors of major toxicity after theophylline overdose. Shannon, M. Ann. Intern. Med. (1993) [Pubmed]
  3. Use of charcoal hemoperfusion with sequential hemodialysis to reduce serum methotrexate levels in a patient with acute renal insufficiency. Molina, R., Fabian, C., Cowley, B. Am. J. Med. (1987) [Pubmed]
  4. Chlorpropamide overdose in renal failure: management with charcoal hemoperfusion. Ludwig, S.M., McKenzie, J., Faiman, C. Am. J. Kidney Dis. (1987) [Pubmed]
  5. Changes in phenytoin concentrations in blood and cerebrospinal fluid caused by direct hemoperfusion in a patient intoxicated with phenytoin. Kanayama, Y., Itakura, Y., Iwasaki, M., Hirahara, Y., Takasino, S., Kawase, Y., Katoh, H., Kinosita, M., Matsumura, O., Mitarai, T., Isoda, K. Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis. (1998) [Pubmed]
  6. Management of theophylline intoxication with charcoal-column hemoperfusion. Russo, M.E. N. Engl. J. Med. (1979) [Pubmed]
  7. Failure of hemoperfusion in digoxin overdose. Rowett, D.A. JAMA (1980) [Pubmed]
  8. Camphor intoxication treated by resin hemoperfusion. Kopelman, R., Miller, S., Kelly, R., Sunshine, I. JAMA (1979) [Pubmed]
  9. Liver support systems: the low clearance of model hepatic excretory anions by charcoal hemoperfusion. Hew, J.T., Hart, F.E., Willson, R.A. Gastroenterology (1978) [Pubmed]
  10. Verapamil toxicity--treatment with hemoperfusion. Rosansky, S.J. Ann. Intern. Med. (1991) [Pubmed]
  11. Caffeine poisoning treated by hemoperfusion. Nagesh, R.V., Murphy, K.A. Am. J. Kidney Dis. (1988) [Pubmed]
  12. Continuous arteriovenous hemoperfusion in acute poisoning. Lin, J.L., Lim, P.S. Blood Purif. (1994) [Pubmed]
  13. Life-threatening diphenhydramine overdose treated with charcoal hemoperfusion and hemodialysis. Mullins, M.E., Pinnick, R.V., Terhes, J.M. Annals of emergency medicine. (1999) [Pubmed]
  14. Reduced systemic drug exposure by combining intra-arterial chemotherapy with hemoperfusion of regional venous drainage. Oldfield, E.H., Dedrick, R.L., Yeager, R.L., Clark, W.C., DeVroom, H.L., Chatterji, D.C., Doppman, J.L. J. Neurosurg. (1985) [Pubmed]
  15. Direct hemoperfusion using a polymyxin B immobilized column improves acute respiratory distress syndrome. Tsushima, K., Kubo, K., Koizumi, T., Yamamoto, H., Fujimoto, K., Hora, K., Kan-Nou, Y. Journal of clinical apheresis. (2002) [Pubmed]
  16. Regional pharmacokinetics of doxorubicin following hepatic arterial and portal venous administration: evaluation with hepatic venous isolation and charcoal hemoperfusion. Iwasaki, T., Ku, Y., Kusunoki, N., Tominaga, M., Fukumoto, T., Muramatsu, S., Kuroda, Y. Cancer Res. (1998) [Pubmed]
  17. Hemoperfusion in acute camphor poisoning. Köppel, C., Martens, F., Schirop, T., Ibe, K. Intensive care medicine. (1988) [Pubmed]
  18. Thallium poisoning--toxin elimination and therapy in three cases. Heath, A., Ahlmén, J., Branegård, B., Lindstedt, S., Wickström, I., Andersen, O. J. Toxicol. Clin. Toxicol. (1983) [Pubmed]
  19. The effect of continuous veno-venous hemofiltration or direct hemoperfusion with polymyxin B-immobilized fiber on neutrophil respiratory oxidative burst in patients with sepsis and septic shock. Naka, T., Shinozaki, M., Akizawa, T., Shima, Y., Takaesu, H., Nasu, H. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. (2006) [Pubmed]
  20. Resin hemoperfusion: a method of removing circulating thyroid hormones. Burman, K.D., Yeager, H.C., Briggs, W.A., Earll, J.M., Wartofsky, L. J. Clin. Endocrinol. Metab. (1976) [Pubmed]
  21. Clinical pilot study on high-dose intraarterial chemotherapy with direct hemoperfusion under hepatic venous isolation in patients with advanced hepatocellular carcinoma. Ku, Y., Fukumoto, T., Iwasaki, T., Tominaga, M., Samizo, M., Nishida, T., Kuroda, Y., Hirota, S., Sako, M., Obara, H. Surgery (1995) [Pubmed]
  22. Neutrophil adherence during hemoperfusion in fulminant hepatic failure. Altin, M., Hughes, R.D., Williams, R. The International journal of artificial organs. (1982) [Pubmed]
  23. Diagnosis of post-transfusion graft-versus-host disease after formalin-fixation. Ryo, R., Goto, M., Takada, M., Saigo, K., Yamaguchi, N., Hayashi, M., Ito, H., Onoyama, H., Saito, Y., Uchida, S. Int. J. Hematol. (1994) [Pubmed]
  24. The effect of hemoperfusion over uncoated and polymer-coated charcoal on hematological levels in the conscious rat. Ryan, C.J., Courtney, J.M. The International journal of artificial organs. (1982) [Pubmed]
  25. Resin hemoperfusion for treatment of a massive meprobamate overdose. Hoy, W.E., Rivero, A., Marin, M.G., Rieders, F. Ann. Intern. Med. (1980) [Pubmed]
  26. Resin hemoperfusion for ethchlorvynol. Dua, S.L., Nagrawala, I., Thompson, R. Ann. Intern. Med. (1980) [Pubmed]
  27. Hemoperfusion for N-acetylprocainamide intoxication. Borkan, S.C. Ann. Intern. Med. (1986) [Pubmed]
  28. Hemoperfusion for phenylbutazone poisoning. Berlinger, W.G., Spector, R., Flanigan, M.J., Johnson, G.F., Groh, M.R. Ann. Intern. Med. (1982) [Pubmed]
  29. Fixed-bed charcoal hemoperfusion. Treatment of drug overdose. Koffler, A., Bernstein, M., LaSette, A., Massry, S.G. Arch. Intern. Med. (1978) [Pubmed]
  30. Morphology of hDAF (CD55) transgenic pig kidneys following ex-vivo hemoperfusion with human blood. Storck, M., Abendroth, D., Prestel, R., Pino-Chavez, G., Müller-Höker, J., White, D.J., Hammer, C. Transplantation (1997) [Pubmed]
  31. Polymyxin-B stimulates tumor necrosis factor-alpha production by human peripheral blood mononuclear cells. Jaber, B.L., Sundaram, S., Cendoroglo Neto, M., King, A.J., Pereira, B.J. The International journal of artificial organs. (1998) [Pubmed]
  32. Gram-negative bacterial sepsis and sepsis syndrome. Dunn, D.L. Surg. Clin. North Am. (1994) [Pubmed]
  33. Phenytoin intoxication in critically ill patients. De Schoenmakere, G., De Waele, J., Terryn, W., Deweweire, M., Verstraete, A., Hoste, E., Rottey, S., Lameire, N., Colardyn, F. Am. J. Kidney Dis. (2005) [Pubmed]
  34. Ex-vivo hemoperfusion (eHPS) of pig-lungs with whole human blood: effects of complement inhibition with a soluble C1-esterase-inhibitor. Schelzig, H., Simon, F., Krischer, C., Vogel, A., Abendroth, D. Ann. Transplant. (2001) [Pubmed]
  35. Artificial kidneys and clearance calculations. Gibson, T.P., Matusik, E., Nelson, L.D., Briggs, W.A. Clin. Pharmacol. Ther. (1976) [Pubmed]
  36. A novel approach for heavy metal poisoning treatment, a model. Mercury poisoning by means of chelating microspheres: hemoperfusion and oral administration. Margel, S. J. Med. Chem. (1981) [Pubmed]
  37. Removal of cimetidine by peritoneal dialysis, hemodialysis, and charcoal hemoperfusion. Pizzella, K.M., Moore, M.C., Schultz, R.W., Walshe, J., Schentag, J.J. Therapeutic drug monitoring. (1980) [Pubmed]
  38. Severe acute valproic acid intoxication successfully treated with hemodiafiltration without hemoperfusion. Minari, M., Maggiore, U., Tagliavini, D., Rotelli, C., Cabassi, A., David, S., Fiaccadori, E. Annals of emergency medicine. (2002) [Pubmed]
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