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Gene Review: 

RPL37  -  ribosomal protein L37

Homo sapiens

Synonyms: 60S ribosomal protein L37, G1.16, L37
 
 
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Disease relevance of RPL37

 

High impact information on RPL37

  • CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism [2].
  • Transfection revealed more rpL37 mRNA associated with nonphosphorylatable La A(366) than with La S(366), concomitant with La A(366)-specific shift of a fraction of L37 mRNA off polysomes [2].
  • The use of cDNA microarrays and real-time quantitative PCR revealed increased expression of the genes encoding ribosomal proteins L17 and L37 (RPL17 and RPL37) in the male forebrain as a whole [3].
  • DNA sequences of bovine and rat G1.16, clones were 92.8% and 92.2% similar to human G1.16 while the deduced amino acid sequences derived from bovine and rat cDNAs each differed by a single amino acid from the sequence of hG1.16 and the published rat L37 sequence [4].
 

Associations of RPL37 with chemical compounds

References

  1. Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. Barnard, G.F., Staniunas, R.J., Puder, M., Steele, G.D., Chen, L.B. Biochim. Biophys. Acta (1994) [Pubmed]
  2. CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism. Schwartz, E.I., Intine, R.V., Maraia, R.J. Mol. Cell. Biol. (2004) [Pubmed]
  3. Sexually dimorphic expression of the genes encoding ribosomal proteins L17 and L37 in the song control nuclei of juvenile zebra finches. Ping Tang, Y., Wade, J. Brain Res. (2006) [Pubmed]
  4. Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37. Su, S., Bird, R.C. Eur. J. Biochem. (1995) [Pubmed]
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