Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

LHX5 - LIM homeobox 5

Homo sapiens

Synonyms: LIM homeobox protein 5, LIM/homeobox protein Lhx5

Zhao, Y. et al., Green, E.K. et al., Pillai, A. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on LHX5

Lhx1 and Lhx5 are co-expressed in multiple interneuron cell types in the developing spinal cord [1].
By reverse transcriptase polymerase chain reaction, LHX5 transcripts were detected in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum [2].
Genomic structure, chromosomal localization and expression of the human LIM-homeobox gene LHX5 [2].
Fluorescence in situ hybridization mapped the LHX5 gene to chromosome 12, position 12q24.31-24.32 [2].
The human gene was found to contain five exons encoding a protein composed of 402 amino acids that is 98.8% identical to mouse Lhx5 [2].

Other interactions of LHX5

METHODS: We screened the coding and intronic flanking regions of the phenylalanine hydroxylase and LHX5 genes for sequence variation by denaturing high-performance liquid chromatography in individuals from the pedigrees [3].

References

Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord. Pillai, A., Mansouri, A., Behringer, R., Westphal, H., Goulding, M. Development (2007) [Pubmed]
Genomic structure, chromosomal localization and expression of the human LIM-homeobox gene LHX5. Zhao, Y., Hermesz, E., Yarolin, M.C., Westphal, H. Gene (2000) [Pubmed]
Mutational analysis of two positional candidate susceptibility genes for bipolar disorder on chromosome 12q23-q24: phenylalanine hydroxylase and human LIM-homeobox LHX5. Green, E.K., Elvidge, G.P., Owen, M.J., Craddock, N. Psychiatr. Genet. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

LHX5	Bos taurus
LHX5	Canis lupus familiaris
lhx5	Danio rerio
LHX5	Gallus gallus
LHX5	Macaca mulatta
Lhx5	Mus musculus
LHX5	Pan troglodytes
Lhx5	Rattus norvegicus
lhx5	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.