High impact information on PAPOLG

• PAP-2 contains two clip domains at its amino terminus and a catalytic domain at its carboxyl terminus, whereas PAP-1 has only one clip domain [1].
• This enzyme, designated prophenoloxidase-activating proteinase-2 (PAP-2), differs from another PAP, previously isolated from integuments of the same insect (PAP-1) [1].
• PAP-2 mRNA was not detected in naive larval fat body or hemocytes, but it became abundant in these tissues after the insects were injected with bacteria [1].
• A novel nuclear human poly(A) polymerase (PAP), PAP gamma [2].
• Although PAP is present as a single-copy gene in the bell pepper genome, Southern blots using PAP2 as a probe revealed multiple homologous copies [3].

Biological context of PAPOLG

• Analyses of the intronic sequence of PAP2 showed the existence of a 206bp short interspersed repetitive element (SINE) belonging to the Ts family of retrotransposons (Yoshioka et al., 1993) [3].
• The electrical conductivity of the PAP2 copolymer film ( approximately 5x10(-6)S/cm) is in the semiconducting region [4].

References