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Gene Review:

cdk5 - cyclin-dependent kinase 5

Danio rerio

Synonyms: SO:0000704

Kanungo, J. et al., Kanungo, J. et al.

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High impact information on cdk5

These phenotypes were rescued by co-injection of cdk5 mRNA [1].
SiRNA-mediated cdk5 knockdown resulted in a reduction in primary sensory neurons of the trigeminal ganglia of the peripheral nervous system, suggesting that cdk5 plays a crucial role in the development of the peripheral nervous system [2].
In situ hybridization analyses demonstrated that zebrafish cdk5 transcripts are ubiquitously expressed as early as the blastula stage [2].

Analytical, diagnostic and therapeutic context of cdk5

RT-PCR analyses showed equal levels of cdk5 transcripts up to 72h of development [2].

References

Cyclin-dependent kinase 5 influences Rohon-Beard neuron survival in zebrafish. Kanungo, J., Li, B.S., Zheng, Y., Pant, H.C. J. Neurochem. (2006) [Pubmed]
Cloning and characterization of zebrafish (Danio rerio) cyclin-dependent kinase 5. Kanungo, J., Li, B.S., Goswami, M., Zheng, Y.L., Ramchandran, R., Pant, H.C. Neurosci. Lett. (2007) [Pubmed]

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AgaP_AGAP005772	Anopheles gambiae str. PEST
AGOS_AGL242C	Ashbya gossypii ATCC 10895
CDK5	Bos taurus
cdk-5	Caenorhabditis elegans
CDK5	Canis lupus familiaris
Cdk5	Drosophila melanogaster
CDK5	Gallus gallus
CDK5	Homo sapiens
KLLA0D11990g	Kluyveromyces lactis NRRL Y-1140
CDK5	Macaca mulatta
MGG_04660	Magnaporthe oryzae 70-15
Cdk5	Mus musculus
NCU07580	Neurospora crassa OR74A
CDK5	Pan troglodytes
Cdk5	Rattus norvegicus
PHO85	Saccharomyces cerevisiae S288c
pef1	Schizosaccharomyces pombe 972h-
cdk5	Xenopus (Silurana) tropicalis

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