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Gene Review

Hamp2  -  hepcidin antimicrobial peptide 2

Mus musculus

Synonyms: 1810073K19Rik, HEPC2, Hepc2, Hepcidin-2
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High impact information on Hamp2

  • These data provide evidence that hepc2 does not act on iron metabolism like hepc1 and give clues for the identification of amino acids important for the iron-regulatory action of the mature 25-amino acid peptide [1].
  • Hepc2 transgenic mRNA level was found to be very high for all lines compared with the level of hepc1 transgene mRNA necessary to produce severe anemia [1].

Biological context of Hamp2


Other interactions of Hamp2

  • The aim of this study was to examine possible differences in the expression of hepcidin genes (Hamp and Hamp2) between the two strains [3].


  1. Functional differences between hepcidin 1 and 2 in transgenic mice. Lou, D.Q., Nicolas, G., Lesbordes, J.C., Viatte, L., Grimber, G., Szajnert, M.F., Kahn, A., Vaulont, S. Blood (2004) [Pubmed]
  2. Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice. Courselaud, B., Troadec, M.B., Fruchon, S., Ilyin, G., Borot, N., Leroyer, P., Coppin, H., Brissot, P., Roth, M.P., Loréal, O. Blood Cells Mol. Dis. (2004) [Pubmed]
  3. Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice. Krijt, J., Cmejla, R., Sýkora, V., Vokurka, M., Vyoral, D., Necas, E. J. Hepatol. (2004) [Pubmed]
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