Gene Review:
XPNPEP2 - X-prolyl aminopeptidase (aminopeptidase P)...
Homo sapiens
Synonyms:
AEACEI, APP2, Aminoacylproline aminopeptidase, Membrane-bound APP, Membrane-bound AmP, ...
- A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. Duan, Q.L., Nikpoor, B., Dube, M.P., Molinaro, G., Meijer, I.A., Dion, P., Rochefort, D., Saint-Onge, J., Flury, L., Brown, N.J., Gainer, J.V., Rouleau, J.L., Agostoni, A., Cugno, M., Simon, P., Clavel, P., Potier, J., Wehbe, B., Benarbia, S., Marc-Aurele, J., Chanard, J., Foroud, T., Adam, A., Rouleau, G.A. Am. J. Hum. Genet. (2005)
- Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments. Réchards, M., Xia, W., Oorschot, V., van Dijk, S., Annaert, W., Selkoe, D.J., Klumperman, J. Traffic (2006)
- Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25. Sprinkle, T.J., Stone, A.A., Venema, R.C., Denslow, N.D., Caldwell, C., Ryan, J.W. Genomics (1998)
- Cloning, chromosomal sublocalization of the human soluble aminopeptidase P gene (XPNPEP1) to 10q25.3 and conservation of the putative proton shuttle and metal ligand binding sites with XPNPEP2. Sprinkle, T.J., Caldwell, C., Ryan, J.W. Arch. Biochem. Biophys. (2000)
- Guinea pig membrane-bound aminopeptidase P is a member of the proline peptidase family. Denslow, N.D., Ryan, J.W., Nguyen, H.P. Biochem. Biophys. Res. Commun. (1994)
- Physical mapping of nine Xq translocation breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene. Prueitt, R.L., Ross, J.L., Zinn, A.R. Cytogenet. Cell Genet. (2000)
- Cloning and tissue distribution of human membrane-bound aminopeptidase P. Venema, R.C., Ju, H., Zou, R., Venema, V.J., Ryan, J.W. Biochim. Biophys. Acta (1997)
- Stimulus responses and amyloid precursor protein processing in DAMI megakaryocytes. Davies, T.A., Billingslea, A., Johnson, R., Greenberg, S., Ortiz, M., Long, H., Sgro, K., Tibbles, H., Seetoo, K., Rathbun, W., Schonhorn, J., Simons, E.R. J. Lab. Clin. Med. (1997)