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Gene Review

GALNT12  -  polypeptide N-acetylgalactosaminyltransfer...

Homo sapiens

Synonyms: CRCS1, GalNAc-T12, Polypeptide GalNAc transferase 12, Polypeptide N-acetylgalactosaminyltransferase 12, Protein-UDP acetylgalactosaminyltransferase 12, ...
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Disease relevance of GALNT12


High impact information on GALNT12


Other interactions of GALNT12

  • Since mucins are glycoproteins mainly produced in the digestive organs, our results suggest that pp-GalNAc-T12 plays an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs [2].

Analytical, diagnostic and therapeutic context of GALNT12


  1. Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-12 in gastric and colonic cancer cell lines and in human colorectal cancer. Guo, J.M., Chen, H.L., Wang, G.M., Zhang, Y.K., Narimatsu, H. Oncology (2004) [Pubmed]
  2. Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12. Guo, J.M., Zhang, Y., Cheng, L., Iwasaki, H., Wang, H., Kubota, T., Tachibana, K., Narimatsu, H. FEBS Lett. (2002) [Pubmed]
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