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Gene Review

WNT10A  -  wingless-type MMTV integration site family...

Homo sapiens

Synonyms: OODD, Protein Wnt-10a, SSPS, STHAG4
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Disease relevance of WNT10A


High impact information on WNT10A


Chemical compound and disease context of WNT10A


Biological context of WNT10A


Other interactions of WNT10A

  • Rat Wnt6 and human WNT6 showed 97.8% total-amino-acid identity, while rat Wnt10a and human WNT10A showed 95.4% total-amino-acid identity [6].


  1. WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells. Kirikoshi, H., Sekihara, H., Katoh, M. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  2. Up-regulation of WNT10A by tumor necrosis factor alpha and Helicobacter pylori in gastric cancer. Kirikoshi, H., Sekihara, H., Katoh, M. Int. J. Oncol. (2001) [Pubmed]
  3. Expression of WNT10A in human cancer. Kirikoshi, H., Inoue, S., Sekihara, H., Katoh, M. Int. J. Oncol. (2001) [Pubmed]
  4. Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia. Adaimy, L., Chouery, E., Megarbane, H., Mroueh, S., Delague, V., Nicolas, E., Belguith, H., de Mazancourt, P., Megarbane, A. Am. J. Hum. Genet. (2007) [Pubmed]
  5. Proto-oncogene WNT10B is up-regulated by tumor necrosis factor alpha in human gastric cancer cell line MKN45. Saitoh, T., Kirikoshi, H., Mine, T., Katoh, M. Int. J. Oncol. (2001) [Pubmed]
  6. Identification and characterization of rat Wnt6 and Wnt10a genes in silico. Katoh, Y., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
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